Restless legs syndrome is associated with headache-related disabilities in patients with migraine: a prospective 7-year follow-up study

European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies
K SuzukiKoichi Hirata

Abstract

No prospective study has evaluated the impact of restless legs syndrome (RLS) on clinical factors in patients with migraine. We planned a prospective study to assess the impact of RLS comorbid status on clinical factors in patients with migraine. A total of 101 patients with migraine who were evaluated for RLS twice at 7-year intervals in a university hospital setting were included in this study. The RLS group was defined as positive for RLS at either baseline or follow-up and the non-RLS group was defined as negative for RLS at both baseline and follow-up. The Migraine Disability Assessment (MIDAS) questionnaire, Beck Depression Inventory-II (BDI-II), Pittsburgh Sleep Quality Index (PSQI) and Epworth Sleepiness Scale were administered to all patients. The RLS prevalence was 16.8% at baseline and 20.8% at follow-up. Compared with the non-RLS group (n = 27), the RLS group (n = 74) showed a significantly higher rate of smoking and higher MIDAS and BDI-II scores at 7-year follow-up. A significant reduction in MIDAS and BDI-II scores at 7-year follow-up compared with those at baseline was observed in the non-RLS group, but not in the RLS group. The non-RLS group showed a significantly lower MIDAS score at 7-year follow-up than the ...Continue Reading

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Citations

Jun 4, 2020·Neuroradiology·Arzu AldemirSelçuk Çomoğlu
Jul 29, 2019·Current Neurology and Neuroscience Reports·Semiha Kurt
Nov 6, 2020·Journal of Neurology·Keisuke SuzukiKoichi Hirata
Jul 16, 2021·The Journal of Headache and Pain·Valeria CaponnettoUNKNOWN European Headache Federation School of Advanced Studies (EHF-SAS)

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