Restoration of normal colonic motor patterns and meal responses after distal colorectal resection

The British Journal of Surgery
R VatherI P Bissett

Abstract

Colorectal resections alter colonic motility, including disruption of control by neural or bioelectrical cell networks. The long-term impact of surgical resections and anastomoses on colonic motor patterns has, however, never been assessed accurately. Fibreoptic high-resolution colonic manometry was employed to define motility in patients who had undergone distal colorectal resection. Recruited patients had undergone distal colorectal resections more than 12 months previously, and had normal bowel function. Manometry was performed in the distal colon (36 sensors; 1-cm intervals), with 2-h recordings taken before and after a meal, with comparison to controls. Analysis quantified all propagating events and frequencies (cyclical, short single, and long single motor patterns), including across anastomoses. Fifteen patients and 12 controls were recruited into the study. Coordinated propagating events directly traversed the healed anastomoses in nine of 12 patients with available data, including antegrade and retrograde cyclical, short single and long single patterns. Dominant frequencies in the distal colon were similar in patients and controls (2-3 cycles/min) (antegrade P = 0·482; retrograde P = 0·178). Compared with values before...Continue Reading

References

Apr 1, 1991·Diseases of the Colon and Rectum·G BatignaniF Tonelli
Sep 1, 1993·International Journal of Colorectal Disease·A F HorganW O Kirwan
Apr 1, 1996·Journal of Gastroenterology and Hepatology·S J BrookesD W King
Jul 26, 2000·Diseases of the Colon and Rectum·A HugeE C Jehle
Mar 20, 2001·American Journal of Physiology. Gastrointestinal and Liver Physiology·S S RaoK Ackerson
Jun 10, 2003·The Journal of Comparative Neurology·Menachem HananiMaria-Simonetta Faussone-Pellegrini
Mar 29, 2008·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·M CamilleriT R Koch
Nov 8, 2008·American Journal of Physiology. Gastrointestinal and Liver Physiology·Jan D Huizinga, Wim J E P Lammers
Mar 10, 2009·Gastroenterology·Hyun-Tai LeeTerence K Smith
Aug 21, 2010·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·P J Gomez-PinillaG Farrugia
Oct 8, 2011·Diseases of the Colon and Rectum·A SharmaI P Bissett
Sep 1, 2012·The Lancet Oncology·Catherine L C BryantChristopher L H Chan
Oct 13, 2012·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·A E Bharucha
Jun 19, 2013·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·P G DinningJ W Arkwright
Feb 25, 2014·Nature Communications·Jan D HuizingaDavid Chen
Apr 24, 2014·Clinical and Experimental Pharmacology & Physiology·Ryash VatherPhil G Dinning
Aug 5, 2014·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·N Mañé, M Jimenez
Aug 19, 2014·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·P G DinningM Costa
Oct 19, 2014·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Cameron I WellsIan P Bissett
Jan 6, 2015·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·P G DinningP A Bampton
Aug 8, 2015·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·P DuG O'Grady

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Citations

Apr 19, 2017·Clinical and Experimental Pharmacology & Physiology·Anthony Y LinGregory O'Grady
Jun 9, 2017·Expert Review of Gastroenterology & Hepatology·Daniele MandolesiLorenzo Fuccio
Mar 25, 2017·American Journal of Physiology. Gastrointestinal and Liver Physiology·Anthony Y LinGregory O'Grady
Jul 5, 2018·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·P G Dinning
Jul 25, 2018·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·I J N KoppenP G Dinning
Sep 14, 2018·The British Journal of Surgery·H ElfekiS Laurberg
Aug 14, 2019·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Cameron I WellsGreg O'Grady
Jul 26, 2019·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·M van HeinsbergenJ L Konsten
Aug 10, 2019·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·M van HeinsbergenJ L Konsten
Mar 4, 2020·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Maham PervezJan D Huizinga
Jun 15, 2017·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·C KeaneI P Bissett
Dec 1, 2020·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Celia KeaneGreg O'Grady

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