Restoring cell polarity: an HSC fountain of youth

Cell Stem Cell
Carmen Carrillo-García, Viktor Janzen

Abstract

Until recently, aging was viewed as a fixed and irreversible process. However, in this issue of Cell Stem Cell, Florian et al. (2012) reveal a link between increased activity of the RhoGTPase Cdc42, hematopoietic stem cell polarity, and aging that can be regulated by pharmacological inhibition of Cdc42.

Citations

Apr 16, 2013·Nature Reviews. Immunology·Hartmut GeigerM Carolina Florian
Sep 21, 2020·Aging Cell·Yixuan FangJianrong Wang
Nov 30, 2014·Biomaterials Science·C Lee-Thedieck, J P Spatz

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.