PMID: 6159926Nov 14, 1980Paper

Restriction mapping of synthetic thyroglobulin structural gene as a means of investigating thyroglobulin structure

Biochimica Et Biophysica Acta
G Vassart, H Brocas

Abstract

Bovine 33 S thyroglobulin mRNA was reverse transcribed into double-stranded DNA under conditions allowing the synthesis of a complete 8 kilobase pair copy. A physical map of the resulting synthetic thyroglobulin structural gene was constructed using six restriction endonucleases. The following conclusions could be drawn: (i) the polypeptide chains in thyroglobulin subunits are identical; (ii) thyroglobulin is composed of a major class of molecules sharing the same primary structure; (iii) there is no evidence for precise internal repetition in the structure of thyroglobulin subunits.

References

Aug 9, 1979·The New England Journal of Medicine·A J Van HerleJ E Dumont
Aug 2, 1979·The New England Journal of Medicine·A J Van HerleJ E Dumont
Jun 15, 1978·European Journal of Biochemistry·C MarriqS Lissitzky
Jun 1, 1977·The Journal of Clinical Investigation·M Izumi, P R Larsen
Sep 1, 1976·Nucleic Acids Research·H O Smith, M L Birnstiel
Nov 7, 1977·Biochemical and Biophysical Research Communications·J ChebathS Lissitzky
Oct 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·G VassartJ E Dumont
Jan 1, 1976·Analytical Biochemistry·J M Bailey, N Davidson
Apr 20, 1973·Biochimica Et Biophysica Acta·M RollandS Lissitzky
Jul 1, 1972·Archives of Biochemistry and Biophysics·J M BilstadG Salvatore
Apr 14, 1980·Biochemical and Biophysical Research Communications·G de MartynoffG Vassart

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Citations

Mar 20, 1999·Biochimica Et Biophysica Acta·V Deshpande, S G Venkatesh
Apr 25, 1983·Nucleic Acids Research·G J van OmmenJ J de Vijlder
Feb 1, 1984·Journal of Endocrinological Investigation·S Lissitzky
Jul 28, 2006·Clinica Chimica Acta; International Journal of Clinical Chemistry·Carina M Rivolta, Héctor M Targovnik
Jan 30, 1984·Biochemical and Biophysical Research Communications·A B RawitchJ W Hamilton
Apr 14, 1982·Biochemical and Biophysical Research Communications·D ChristopheG Vassart
Apr 16, 1984·European Journal of Biochemistry·C M NepokroeffJ W Porter
May 4, 1987·European Journal of Biochemistry·G de MartynoffG Vassart
Aug 14, 1992·Biochemical and Biophysical Research Communications·F GentileG Salvatore
Nov 1, 1981·European Journal of Biochemistry·J L Bergé-LefrancS Lissitzky
Mar 1, 1982·European Journal of Biochemistry·D ChristopheG Vassart
Feb 1, 1989·Biochimie·Y MalthièryS Lissitzky
Jul 26, 1982·Biochimica Et Biophysica Acta·C DavoliH Edelhoch
Jul 1, 1985·Molecular and Cellular Endocrinology·Y KondoN Ui
May 1, 1985·Molecular and Cellular Endocrinology·G VassartH Targovnik

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