PMID: 7037160Mar 15, 1982Paper

Results in patients with breast cancer treated by radical mastectomy and postoperative irradiation with no adjuvant chemotherapy

Cancer
N D TapleyM J Oswald

Abstract

In 1963 an electron beam became available, making irradiation of the chest wall technically easy. In addition to peripheral lymphatic irradiation in patients with positive axillary nodes and/or the tumor in the inner quadrants or centrally located, patients with tumor larger than 5 cm or with grave signs and/or a significant incidence of positive axillary nodes received chest wall irradiation. None of the patients has received elective chemotherapy. Disease-free survival rates at ten years are 54% for the overall group, 79% for the patients with negative nodes, 44% for patients with positive nodes, 61% for patients with 1-3 positive nodes, and 33% for patients with four or more positive nodes. The incidence of peripheral lymphatic failures is low as well as the incidence of failures on the chest wall in the patients having had chest wall irradiation. With the availability of electron beam and adjustments in doses, complications are nonexistent. The incidence of treatment failures, local-regional, or distant, that have appeared by ten years are compared with the incidence of failures that were experienced by the placebo patients in the clinical trial of the NSABP of thio-TEPA versus placebo. The clearly lesser incidence of treat...Continue Reading

References

May 1, 1978·International Journal of Radiation Oncology, Biology, Physics·G H Fletcher, E D Montague
Nov 1, 1977·International Journal of Radiation Oncology, Biology, Physics·H Høst, I O Brennhovd
Jan 1, 1971·The American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine·G H Fletcher
May 1, 1981·International Journal of Radiation Oncology, Biology, Physics·J M BedwinekM Ocwieza
Mar 1, 1980·International Journal of Radiation Oncology, Biology, Physics·A WallgrenC Silfverswärd
Oct 1, 1981·International Journal of Radiation Oncology, Biology, Physics·L E StrenderC Silfverswärd

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Citations

Jan 1, 1984·Breast Cancer Research and Treatment·G F Beadle, J R Harris
Aug 1, 1985·Seminars in Oncology Nursing·K M Hassey
Nov 1, 1983·International Journal of Radiation Oncology, Biology, Physics·B F DanoffT F Pajak
Jul 1, 1989·International Journal of Radiation Oncology, Biology, Physics·G H FletcherM J Oswald
Dec 1, 1985·International Journal of Radiation Oncology, Biology, Physics·G H Fletcher
Jan 1, 1988·International Journal of Radiation Oncology, Biology, Physics·J Boyages, A O Langlands
Jan 1, 1986·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·S LeungB Pierquin
Oct 1, 1983·Current Problems in Cancer·G H Fletcher
Dec 21, 2013·CA: a Cancer Journal for Clinicians·Reshma Jagsi
Mar 15, 1984·Cancer·G H Fletcher
Dec 2, 2017·Annual Review of Medicine·Julie A Bradley, Nancy P Mendenhall
Feb 1, 1990·Disease-a-month : DM·L F HutchinsK C Westbrook

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