PMID: 11337299May 19, 2001Paper

Results of a screening program for prostate cancer in patients scheduled for abdominoperineal resection for colorectal pathologic findings

Urology
M K Terris, S M Wren

Abstract

Because of the difficulty of accessing the prostate for tissue sampling after surgical removal of the rectum and obliteration of the anus, we started an early detection program for prostate cancer in all men scheduled for abdominoperineal resection. Twenty consecutive men were screened for prostatic adenocarcinoma before planned abdominoperineal resection for colorectal pathologic findings. Patients were 48 to 77 years old (mean 66.9). Screening included serum prostate-specific antigen determination and digital rectal examination. Those patients with suspicious findings underwent transrectal ultrasound-guided sextant biopsies of the prostate. One patient was excluded because of a prior history of prostate cancer. Six (31.6%) of the remaining 19 patients demonstrated elevated prostate-specific antigen levels (greater than 4.0 ng/mL); two of these patients also had an abnormal digital rectal examination. Transrectal ultrasound and prostate biopsies in these 6 patients revealed prostatic adenocarcinoma in 3 patients (50% of those undergoing biopsies or 15.8% of those screened). The 13 patients who did not undergo prostate biopsies had prostate-specific antigen levels from 0.4 to 2.4 ng/mL (mean 0.9) and normal prostate glands acco...Continue Reading

References

May 1, 1994·Urology·P S Filderman, S C Jacobs
Jun 1, 1996·AJR. American Journal of Roentgenology·N PapanicolaouA F Althausen
Oct 8, 1999·Urology·L W Klee, P Grmoljez
Oct 8, 1999·Urology·R Shinghal, M K Terris
Mar 16, 2000·Journal of the National Cancer Institute
Jul 14, 2000·The Journal of Urology·A V D'AmicoJ P Richie

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Citations

Mar 28, 2012·International Journal of Colorectal Disease·D O KavanaghD C Winter
Apr 1, 2015·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·E BuscailQ Denost
Aug 22, 2015·AJR. American Journal of Roentgenology·Ajit H GoenkaEric A Klein
Feb 2, 2015·European Journal of Radiology·Margrét SturludóttirLennart Blomqvist
Feb 14, 2008·International Journal of Urology : Official Journal of the Japanese Urological Association·Koji OkiharaTsuneharu Miki
Sep 20, 2008·The Journal of Urology·Cheryn SongUNKNOWN Korean Urological Oncology Society
Apr 9, 2020·Frontiers in Oncology·Corbin D JacobsBrian G Czito

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