Results of electrophysiologic studies in patients with acute Chagasic myocarditis

Clinical Cardiology
A J FuenmayorD Jugo

Abstract

As the acute stage of Chagas' myocarditis is rarely detected, little is known about the electrophysiologic characteristics of that stage. This investigation was undertaken to conduct an electrophysiologic study of the properties of the heart during the acute phase of Chagasic myocarditis. We studied eight patients who had positive xenodiagnosis, positive mice culture, and positive complement fixation test for Chagas' disease. Trypanosoma cruzi were identified in all of the patients' stained blood samples. Right ventricular endomyocardial biopsies were obtained, evidencing a distinct infiltrate of lymphocytes that confirmed the diagnosis of acute myocarditis. The cardiac dimensions and the ventricular systolic and diastolic function were preserved in all patients. The electrocardiogram evidenced conduction defects in two patients. The signal-averaged electrocardiogram displayed late potentials in three patients. In the electrophysiologic study, atrial fibrillation or flutter was induced in four patients. When compared with control patients, Chagasic patients were found to have greater values of atrial threshold, A-H interval, and atrioventricular (AV) nodal effective refractory period. The H-V interval was mildly prolonged in tw...Continue Reading

Citations

Nov 15, 2001·Transactions of the Royal Society of Tropical Medicine and Hygiene·L B GuerraC R Machado
Jun 21, 2016·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Andreas GoetteStanley Nattel
Sep 3, 2016·Journal of Arrhythmia·Andreas GoetteUNKNOWN Review coordinator: Alena Shantsila (UK)
Jul 13, 2016·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Andreas GoetteUNKNOWN Document Reviewers:
May 2, 2002·Pediatrics International : Official Journal of the Japan Pediatric Society·Yukio KuramochiShunichi Ogawa
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