PMID: 9554530Apr 29, 1998Paper

Results of intermediate measures from a population-based, randomized trial of mammographic screening prevalence and detection of breast carcinoma among Asian women: the Singapore Breast Screening Project

Cancer
E H NgC C Wilde

Abstract

Although increasing rates of breast carcinoma incidence have been observed in Asian countries, appropriate strategies for detecting early stage breast carcinoma in such communities have been difficult to formulate, particularly because no large population screening trial specifically involving Asian women has been reported. The objective of this study was to evaluate the effectiveness and quality of mammography as a screening technique for Singaporean women, who are predominantly Chinese. In this prospective study, 166,600 women in Singapore ages 50-64 years were randomized to either 2-view mammography without physical examination (67,656) or observation (97,294, controls) over 2 years. Of these women, 28,231 (41.7%) responded and were screened; they were more likely to be married, have more formal education, be working, be Chinese, and be in a higher socioeconomic group (P < 0.001 for all variables). To assess for response bias that could affect outcome, results were also evaluated for nonrespondents (n = 39,425). The incidence rate of cancers among nonrespondents (1 per 1000 woman-years) was less than the 1.3 in women not invited to have screening (P = 0.03, relative risk [RR], 1.3; 95% confidence interval [CI], 1.0-1.7). How...Continue Reading

Citations

Oct 31, 2002·American Journal of Public Health·Gabriel M LeungAnthony J Hedley
Dec 10, 2008·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Anna H WuMimi C Yu
Feb 4, 2012·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Eunjung LeeAnna H Wu
Oct 20, 2015·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Hui Shan TanWei-Yen Lim
Jan 18, 2008·ANZ Journal of Surgery·Esther W L ChuwaChow-Yin Wong
Sep 12, 2006·Cytopathology : Official Journal of the British Society for Clinical Cytology·I ChewP H Tan
Nov 4, 2006·The Breast : Official Journal of the European Society of Mastology·S M TanK L Cheung

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