Results of Open Surgical Repair in Patients With Marfan Syndrome and Distal Aortic Dissection

The Annals of Thoracic Surgery
Joseph S CoselliScott A LeMaire

Abstract

In patients with Marfan syndrome (MFS), distal aortic dissection can necessitate thoracoabdominal aortic aneurysm (TAAA) repair in survivors of acute DeBakey type I dissection and those with DeBakey type III dissection. We examined outcomes of surgical repair of TAAA in patients with MFS with distal aortic dissection. Data were analyzed for 127 consecutive TAAA repairs performed between January 2004 and June 2014 in patients with MFS and distal aortic dissection-DeBakey types I (n = 73) and III (n = 54). The median time from dissection onset to TAAA repair was 5.2 years (interquartile range [IQR]: 2.1 to 9.8 years) for the overall group and was longer in patients with DeBakey I (6.5 years, IQR: 3.5 to 13.9 years) than patients with DeBakey III (2.9 years, IQR: 0.6 to 6.0 years, p < 0.001). Eleven patients (9%) had acute or subacute dissection at the time of repair. Sixty-six patients (52%) underwent Crawford extent II TAAA repair. A composite end point, adverse event, was defined as operative death or permanent stroke, renal failure, paraplegia, or paraparesis. Eight patients had adverse events (6%), including 5 operative deaths (4%). There was no permanent stroke and 1 case each of permanent paraplegia and paraparesis. At disc...Continue Reading

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Citations

Jul 30, 2019·The Journal of International Medical Research·Amer HarkyAhmed Al-Adhami
Jun 27, 2018·The Journal of Cardiovascular Surgery·Giovanni TinelliStéphan Haulon
Aug 11, 2020·Asian Cardiovascular & Thoracic Annals·Davut ÇekmeceliogluJoseph S Coselli
Apr 4, 2018·General Thoracic and Cardiovascular Surgery·Kenji MinatoyaJunjiro Kobayashi
Jun 1, 2019·Indian Journal of Thoracic and Cardiovascular Surgery : Official Organ, Association of Thoracic and Cardiovascular Surgeons of India·Jeremy R LeonardLeonard N Girardi
Oct 31, 2020·Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery·Jonathan C HongOurania Preventza
Mar 25, 2021·Seminars in Vascular Surgery·Sherene ShalhubKarina Newhall
Dec 23, 2019·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·Quentin PellencYves Castier
Jul 17, 2019·The Journal of Thoracic and Cardiovascular Surgery·Yuki IkenoYutaka Okita
Jul 5, 2021·The Journal of Thoracic and Cardiovascular Surgery·Rodolfo V RochaStephen E Fremes
Jan 9, 2019·Journal of Vascular Surgery Cases and Innovative Techniques·Georgios KaraolanisKonstantinos P Donas
Sep 17, 2017·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·Paula R KeschenauMichael J Jacobs

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