Results of operative management of Crohn's disease: A series of 50 patients managed by one surgeon

Diseases of the Colon and Rectum
F T McDermottA B Price

Abstract

A computer analysis has been made of clinical experience of Crohn's disease in Australian patients. Between 1950 and 1978, 50 patients were managed for Crohn's disease by one of the authors (E.S.R.H.). This group represented 3.1 per cent of 1608 patients treated during the same period for primary inflammatory bowel disease. The mean follow-up period was 8.4 years. Thirty-nine of the 50 patients were female and 11 male. The small intestine was involved in seven patients, large intestine in 17 and both small and large intestine in 26. Symptoms were related to the anatomic localization of disease. Four patients have died (two postoperative deaths and two unrelated to Crohn's disease). Forty-nine of the 50 patients required operative procedures and 36 underwent one or more definitive operations with curative intention. A total of 124 operations was performed, 70 of which were definitive. Twenty-nine of the 36 patients managed by a definitive operation developed recurrence, defined to include reactivation of disease in intestinal segments left in situ. Ten patients developed two or more recurrences. Multiple recurrences were most frequent after operation for combined small- and large-intestinal Crohn's disease. No patient with large...Continue Reading

References

Apr 1, 1979·Australian and New Zealand Journal of Medicine·W S SelbyN D Gallagher
Sep 1, 1979·Diseases of the Colon and Rectum·E S HughesJ P Masterton
Oct 2, 1975·The New England Journal of Medicine·A J GreensteinH D Janowitz
Jul 1, 1975·The British Journal of Surgery·S YoungG Gillespie
Mar 1, 1976·Gut·S C Truelove, A S Pena
May 30, 1970·Lancet·P PriorW T Cooke
Oct 1, 1972·The British Journal of Surgery·F T De Dombal
Nov 1, 1971·The British Journal of Surgery·F T De DombalJ C Goligher
Apr 1, 1968·Gut·V J McGovern, S J Goulston
Jan 1, 1958·Gastroenterologia·B B CROHN

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Citations

Dec 1, 1991·Scandinavian Journal of Gastroenterology·A Wettergren, J Christiansen
Sep 2, 2004·Alimentary Pharmacology & Therapeutics·F L WoltersR W Stockbrügger
Jan 1, 1991·The British Journal of Surgery·J G WilliamsS M Goldberg
Aug 1, 1995·The Australian and New Zealand Journal of Surgery·P F Anseline
Nov 1, 1982·World Journal of Surgery·E Schmidt

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