Results of surgical management of 319 pituitary adenomas

Acta neurochirurgica
B GuidettiG Cantore

Abstract

Of the 510 patients with pituitary adenoma treated surgically at our hospital in the period 1956-1984 319 were treated by the microsurgical technique, in the period 1973-1984, 235 by transsphenoidal approach and 84 by subfrontal-pterional approach. The transsphenoidal route was used almost exclusively in microadenomas, in intrasellar adenomas, in suprasellar adenomas with midline development, in adenomas invading the sphenoidal sinus and in haemorrhagic adenomas with considerable suprasellar development. In some giant adenomas the transsphenoidal route was used in a first stage operation for debulking the tumour, later removed by transcranial route. The latter route was preferred in large adenomas and especially in adenomas with laterosellar development. In some patients with PRL secreting adenomas post-operative treatment with bromocriptine proved useful when the hormone levels failed to normalize. Post-operative radiotherapy was of value in invasive adenomas and in cases in which tumour removal was not radical.

References

Jan 1, 1978·Journal of Neurosurgery·C B Wilson, L C Dempsey
Jun 1, 1976·Journal of Neurosurgery·M A GiovanelliG Faglia
Jan 1, 1985·Neurosurgical Review·Rudolf Fahlbusch, M Buchfelder
Jan 1, 1985·Neurosurgical Review·H W PiaG Hildebrandt
Feb 1, 1984·Current Problems in Cancer·Edward Laws
Jan 1, 1983·Acta neurochirurgica·M ScanariniD Billeci
Jan 1, 1984·Journal of Neurosurgery·Daniel Louis BarrowJ C Hoffman
Oct 1, 1983·Journal of Neurosurgery·B FraioliP Celli
Sep 1, 1982·Journal of Neurology, Neurosurgery, and Psychiatry·L SymonS Mohanty
Aug 1, 1981·Journal of Neurosurgery·S WakaiK Sano
Oct 1, 1981·Journal of Neurosurgery·N A MartinC B Wilson
Oct 1, 1981·The Journal of Clinical Endocrinology and Metabolism·P ChiodiniR Horowski

Citations

Jan 1, 1994·Neurosurgical Review·B FraioliG Cantore
Apr 19, 2008·Pituitary·M Buchfelder, Juergen Kreutzer
Oct 19, 2012·Pituitary·Ravindran PratheeshAri G Chacko
Mar 19, 2013·Clinical Neurology and Neurosurgery·Hidetoshi IkedaTakashi Yoshimoto
Aug 1, 1997·Surgical Oncology·P J Yeh, J W Chen
Jul 26, 2012·Systematic Reviews·Amy T WangMohammad Hassan Murad
Feb 10, 2009·Journal of Neurosurgery·Abtin TabaeeTheodore H Schwartz
Nov 30, 1999·Journal of Neurosurgery·M A Sánchez-VázquezF Sanchez-Herrera
Feb 19, 2014·European Journal of Endocrinology·Dominique Maiter, Etienne Delgrange
Sep 29, 2006·Expert Review of Anticancer Therapy·Wael MuslehMaciej S Lesniak
Jan 11, 1992·British Journal of Neurosurgery·P CarboniR Postans
Dec 1, 2009·Best Practice & Research. Clinical Endocrinology & Metabolism·Annamaria Colao
Oct 16, 2010·Neurosurgery Clinics of North America·Isaac YangMarvin Bergsneider
Sep 7, 1996·The Veterinary Record·I Marco-SánchezS Lavín
May 1, 1989·World Journal of Surgery·B EisemanB Borlase
May 11, 2010·Current Opinion in Endocrinology, Diabetes, and Obesity·Kiarash ShahlaieDaniel F Kelly
May 18, 2006·Endocrine Reviews·Mary P GillamAnnamaria Colao
Sep 19, 1998·American Journal of Rhinology·M R AustJ Atkinson

Related Concepts

Adenoma, Trabecular
Teens
Combined Modality Therapy
Hypophysectomy
Microsurgery
Pituitary Irradiation
Pituitary Carcinoma

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