Results of surgical treatment for familial polyposis coli

American Journal of Surgery
T M HeimannA H Aufses

Abstract

Seventy-seven patients with polyposis coli operated on at The Mount Sinai Hospital in the last 40 years were studied. Forty-two patients had a subtotal colectomy. Sixteen were found to have colon cancer at the time of operation, and a second rectal cancer developed in 50 percent of the survivors within 1 to 13 years after subtotal colectomy. Rectal cancer subsequently developed in only 3 of 23 patients without colon cancer. Thirty-five patients had total proctocolectomy or total colectomy with mucosal proctectomy and ileoanal anastomosis. Recurrent adenomatous polyps developed in two patients after mucosal proctectomy. A villous adenoma with carcinoma in situ of the ileum developed in one patient 30 years after total proctocolectomy and ileostomy. Another patient died from a periampullary carcinoma 24 years after subtotal colectomy. It seems that as the life expectancy of patients with polyposis improves, the incidence of small bowel and duodenal cancers may be expected to increase.

References

May 1, 1975·The British Journal of Surgery·B Leppard, H J Bussey
Mar 12, 1973·JAMA : the Journal of the American Medical Association·P L SchnurE G Harrison
Sep 1, 1974·Cancer·J UtsunomiyaT Ichikawa
Oct 1, 1980·Diseases of the Colon and Rectum·J UtsunomiyaR Hirayama
May 1, 1983·American Journal of Surgery·T HeimannI Kreel
Apr 1, 1980·Archives of Surgery·M A BessC G Moertel

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Citations

Aug 1, 1989·International Journal of Colorectal Disease·J F SlorsW H Brummelkamp
May 1, 1992·Diseases of the Colon and Rectum·F MillerT M Fasy
Mar 1, 1997·Diseases of the Colon and Rectum·Y S JangT M Heimann
Sep 1, 1988·Diseases of the Colon and Rectum·R L NelsonH Abcarian
Jun 1, 1989·Diseases of the Colon and Rectum·T M HeimannA H Aufses
Nov 26, 2009·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Tomohiro YamaguchiYoshihiro Moriya
Jul 1, 1989·Baillière's Clinical Gastroenterology·J M Northover, V Murday
Dec 1, 1989·Annals of Surgery·T M HeimannA J Greenstein
Feb 27, 2010·Journal of Pediatric Hematology/oncology·John A D'Orazio
Oct 1, 1996·Gastrointestinal Endoscopy·A GellerK P Batts
Jun 1, 1987·Diseases of the Colon and Rectum·T M HeimannA R Beck

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