Resuscitation and post resuscitation care of the very old after out-of-hospital cardiac arrest is worthwhile

International Journal of Cardiology
Matilde Winther-JensenHelle Søholm

Abstract

Out-of-hospital cardiac arrest (OHCA) is associated with a poor prognosis. As comorbidity and frailty increase with age; ethical dilemmas may arise when OHCA occur in the very old. We aimed to investigate mortality, neurological outcome and post resuscitation care in octogenarians (≥80) to assess whether resuscitation and post resuscitation care should be avoided. During 2007-2011 consecutive OHCA-patients were attended by the physician-based Emergency Medical Services-system in Copenhagen. Pre-hospital data based on Utstein-criteria, and data on post resuscitation care were collected. Primary outcome was successful resuscitation; secondary endpoints were 30-day mortality and neurological outcome (Cerebral Performance Category (CPC)). 2509 OHCA-patients with attempted resuscitation were recorded, 22% (n=558) were octogenarians/nonagenarians. 166 (30% of all octogenarians with resuscitation attempted) octogenarians were successfully resuscitated compared to 830 (43% with resuscitation attempted) patients <80 years. 30-day mortality in octogenarians was significantly higher after adjustment for prognostic factors (HR=1.61 CI: 1.22-2.13, p<0.001). Octogenarians received fewer coronary angiographies (CAG) (14 vs. 37%, p<0.001), and...Continue Reading

References

Aug 5, 2000·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·R A SworR G Pirrallo
Dec 9, 2000·Archives of Internal Medicine·C KimM S Eisenberg
Sep 20, 2002·Journal of Epidemiology and Community Health·R A RaineD A Wood
Apr 9, 2004·Critical Care Medicine·T Jared BunchDouglas L Packer
Mar 31, 2005·Journal of Neurosurgery·Marek CzosnykaJohn D Pickard
Sep 1, 2005·Resuscitation·Audun LanghelleUNKNOWN 2003 Utstein Consensus Symposium
Dec 3, 2005·Resuscitation·Jerry Nolan, UNKNOWN European Resuscitation Council
Jan 31, 2006·American Heart Journal·Raymond T YanUNKNOWN Canadian Acute Coronary Syndromes (ACS) Registry Investigators
Mar 6, 2007·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Bart RypmaDonovan Rebbechi
Sep 4, 2008·Proceedings of the National Academy of Sciences of the United States of America·Adam GazzaleyMark D'Esposito
Nov 26, 2008·The American Journal of Cardiology·R Bhullar SidhuCraig A Thompson
Mar 31, 2009·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Terry Therneau
May 26, 2009·The American Journal of Cardiology·Alan J BagnallUNKNOWN Canadian Global Registry of Acute Coronary Events (GRACE/GRACE2) Investigators
Jun 25, 2009·Acta Anaesthesiologica Scandinavica·N NielsenUNKNOWN Hypothermia Network
Aug 4, 2010·Archives of Gerontology and Geriatrics·Miloslav PleskotEva Cermakova
Dec 16, 2010·Proceedings of the National Academy of Sciences of the United States of America·Lars NybergLars-Göran Nilsson
Feb 4, 2011·Resuscitation·C DeasyUNKNOWN VACAR Steering Committee
Aug 4, 2011·Scandinavian Journal of Public Health·Elsebeth LyngeMatejka Rebolj
Oct 5, 2011·Circulation·Lance B BeckerUNKNOWN Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation
Feb 12, 2013·Lancet·Andrew CleggKenneth Rockwood
Oct 11, 2013·Critical Care Medicine·David B SederUNKNOWN International Cardiac Arrest Registry (INTCAR)-Cardiology Research Group
May 16, 2014·Circulation. Cardiovascular Quality and Outcomes·Shannon M DunlayVéronique L Roger
Aug 4, 2015·Resuscitation·Marianne AgerskovLars Simon Rasmussen

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Citations

Jul 8, 2016·Scandinavian Cardiovascular Journal : SCJ·Matilde Winther-JensenChristian Hassager
Jun 1, 2017·Nursing Ethics·Mattias KarlssonYvonne Hilli
May 31, 2018·Acta Anaesthesiologica Scandinavica·H KangasniemiS Hoppu
Sep 6, 2018·Scandinavian Cardiovascular Journal : SCJ·Matilde Winther-JensenChristian Hassager
Oct 18, 2019·Geriatrics & Gerontology International·Fumiko NakamuraUNKNOWN CRITICAL Study investigators
Dec 6, 2017·European Journal of Cardiovascular Nursing : Journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology·Eric WielUNKNOWN GR-RéAC
Feb 26, 2021·Emergency Medicine International·Ling Hsuan HuangFu-Jen Cheng
Jun 8, 2021·Notfall & Rettungsmedizin·Spyros D MentzelopoulosLeo Bossaert
Aug 4, 2021·Medizinische Klinik, Intensivmedizin und Notfallmedizin·Kevin Roedl
Jul 22, 2020·Physiology International·E KovácsE Zima

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