Retention on ART and predictors of disengagement from care in several alternative community-centred ART refill models in rural Swaziland

Journal of the International AIDS Society
Lorraine PasipamireBernhard Kerschberger

Abstract

A broad range of community-centred care models for patients stable on anti-retroviral therapy (ART) have been proposed by the World Health Organization to better respond to patient needs and alleviate pressure on health systems caused by rapidly growing patient numbers. Where available, often a single alternative care model is offered in addition to routine clinical care. We operationalized several community-centred ART delivery care models in one public sector setting. Here, we compare retention in care and on ART and identify predictors of disengagement with care. Patients on ART were enrolled into three community-centred ART delivery care models in the rural Shiselweni region (Swaziland), from 02/2015 to 09/2016: Community ART Groups (CAGs), comprehensive outreach care and treatment clubs. We used Kaplan-Meier estimates to describe crude retention in care model and retention on ART (including patients who returned to clinical care). Multivariate Cox proportional hazard models were used to determine factors associated with all-cause attrition from care model and disengagement with ART. A total of 918 patients were enrolled. CAGs had the most participants with 531 (57.8%). Median age was 44.7 years (IQR 36.3 to 54.4), 71.8% of...Continue Reading

References

Mar 31, 2010·The Journal of Infectious Diseases·Nicola E MackieAnna-Maria Geretti
Jun 29, 2013·The Cochrane Database of Systematic Reviews·Tamara KredoPaul Garner
Jun 4, 2014·Tropical Medicine & International Health : TM & IH·Marielle BemelmansNathan Ford
Jun 6, 2014·Tropical Medicine & International Health : TM & IH·Tom DecrooMarie Laga
Jul 30, 2014·Tropical Medicine & International Health : TM & IH·Jeffrey V LazarusShabbar Jaffar
Aug 30, 2014·Psychology, Health & Medicine·Raashika Dudhia, Ashraf Kagee
Jan 15, 2015·Tropical Medicine & International Health : TM & IH·Chris DuncombeGeoff Garnett
Dec 4, 2015·Nature·UNKNOWN Working Group on Modelling of Antiretroviral Therapy Monitoring Strategies in Sub-Saharan AfricaPaul Revill
Apr 14, 2017·Journal of the International AIDS Society·Umberto PellecchiaKennedy Kanyimbo

❮ Previous
Next ❯

Citations

Feb 15, 2020·PLoS Medicine·Nathan FordHelen Bygrave
Apr 3, 2020·Journal of the International AIDS Society·Lynne WilkinsonAnna Grimsrud
Sep 23, 2020·Tropical Medicine & International Health : TM & IH·I FinciL Molfino
Mar 27, 2021·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Nwanneka E OkereGabriela B Gomez

❮ Previous
Next ❯

Software Mentioned

Stata

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.