Rethinking clinical oncology drug research in an era of value-based cancer care: A role for chemotherapy pathways.

Cancer Medicine
J Russell Hoverman

Abstract

The United States spends nearly 1/5th of its GDP on healthcare. Yet, to achieve value-based care, the Economist describes the US healthcare system as handicapped by multiple, disparate silos that prevent the organization and sharing of data. This paper explores the current state of clinical oncology drug research and its relationship to value-based cancer care. Clinical Chemotherapy Pathways are proposed as a unifying structure to bring together disparate sources of data to increase value.

References

May 16, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·F A ShepherdJ Berille
Jan 11, 2002·The New England Journal of Medicine·Joan H SchillerUNKNOWN Eastern Cooperative Oncology Group
Feb 19, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Charles L VogelLee S Schwartzberg
Oct 13, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Vernon HarveySoeren Cold
Dec 15, 2006·The New England Journal of Medicine·Alan SandlerDavid H Johnson
Feb 21, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·John K ChanDaniel S Kapp
Oct 29, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Christopher M BoothMonika K Krzyzanowska
Jul 22, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Christopher M BoothRalph M Meyer
Sep 3, 2009·JAMA : the Journal of the American Medical Association·Sylvain MathieuPhilippe Ravaud
Sep 3, 2011·Journal of Oncology Practice·J Russell HovermanRoy A Beveridge
Dec 14, 2011·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Benoit YouEric X Chen
May 24, 2013·JAMA Internal Medicine·Bradford R HirschAmy P Abernethy
Oct 18, 2013·The New England Journal of Medicine·Daniel D Von HoffMarkus F Renschler
Jul 10, 2014·Journal of Oncology Practice·Lee N NewcomerMonica Perkins
Jul 15, 2015·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Thomas J SmithJames O Armitage
Aug 26, 2015·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Kanwal Pratap Singh RaghavMichael J Overman
Jan 14, 2016·Journal of Oncology Practice·Robin T ZonLinda D Bosserman
Jun 2, 2016·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Lowell E SchnipperRichard L Schilsky
Mar 11, 2017·Journal of Oncology Practice·Lee N Newcomer, Jennifer L Malin
Aug 16, 2017·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Mario EisenbergerJohann de Bono
Feb 27, 2018·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Richard J WillkeScott D Ramsey
Mar 17, 2018·Journal of Oncology Practice·J Russell HovermanDiana K Verrilli
Aug 14, 2018·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Risha Gidwani-MarszowskiSteven M Asch
Oct 23, 2018·The New England Journal of Medicine·Peter SchmidUNKNOWN IMpassion130 Trial Investigators
May 18, 2019·American Society of Clinical Oncology Educational Book·Bassel NazhaTaofeek K Owonikoko
May 29, 2019·JAMA Internal Medicine·Bishal GyawaliAaron S Kesselheim
Jun 4, 2019·JAMA Oncology·Ethan B LudmirC David Fuller
Jun 20, 2019·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Krishnansu S TewariBradley J Monk
Dec 5, 2019·The Lancet Oncology·Vinay Prasad, Christopher M Booth
Mar 21, 2020·JCO Oncology Practice·Andrew HertlerJames Wade
Apr 8, 2020·Journal of the National Comprehensive Cancer Network : JNCCN·Antonious HazimEmerson Y Chen

❮ Previous
Next ❯

Citations

Jul 16, 2021·JCO Oncology Practice·J Russell HovermanMarcus Neubauer

❮ Previous
Next ❯

Software Mentioned

Pathways
Cigna
Humana

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The New England Journal of Medicine
Robert C Young
Journal of Shoulder and Elbow Surgery
Richard C Chad Mather, Kevin J Bozic
Anesthesiology
Yuriy S Bronshteyn
Foot & Ankle International
Michael S Pinzur
The Oncologist
Keith D EatonRenato G Martins
© 2022 Meta ULC. All rights reserved