Rethinking Concepts and Categories for Understanding the Neurodevelopmental Effects of Childhood Adversity.

Perspectives on Psychological Science : a Journal of the Association for Psychological Science
Karen E Smith, Seth D Pollak

Abstract

Discovering the processes through which early adverse experiences affect children's nervous-system development, health, and behavior is critically important for developing effective interventions. However, advances in our understanding of these processes have been constrained by conceptualizations that rely on categories of adversity that are overlapping, have vague boundaries, and lack consistent biological evidence. Here, we discuss central problems in understanding the link between early-life adversity and children's brain development. We conclude by suggesting alternative formulations that hold promise for advancing knowledge about the neurobiological mechanisms through which adversity affects human development.

References

Jun 1, 1975·Journal of Human Stress·J W Mason
Jan 1, 1992·Integrative Physiological and Behavioral Science : the Official Journal of the Pavlovian Society·J P Henry
Jun 6, 1998·Proceedings of the National Academy of Sciences of the United States of America·C CaldjiM J Meaney
May 7, 1997·Quality in Health Care : QHC·C Smith
Jun 7, 2000·Psychoneuroendocrinology·K VedharaS Plummer
Jul 21, 2000·Nature Neuroscience·D LiuM J Meaney
Sep 8, 2000·Developmental Psychology·Seth D PollakAlex Reed
Oct 31, 2002·Human Psychopharmacology·Bruce S. McEwen, Ana Maria Magarinos
Feb 18, 2003·Journal of Neuroendocrinology·A H VeenemaJ M Koolhaas
Jan 1, 2004·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Linda L CarpenterLawrence H Price
Feb 26, 2004·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Jochen Hardt, Michael Rutter
May 5, 2004·Psychological Bulletin·Sally S Dickerson, Margaret E Kemeny
May 6, 2004·Journal of Anxiety Disorders·Metin BaşoğluMaria Livanou
May 12, 2004·Journal of Clinical Child and Adolescent Psychology : the Official Journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53·Kathryn E GrantPolly Y Gipson
Jun 29, 2004·Nature Neuroscience·Ian C G WeaverMichael J Meaney
Oct 20, 2004·Advances in Chronic Kidney Disease·Gail D Anderson, Peggy S Odegard
Jan 22, 2005·Personality and Social Psychology Review : an Official Journal of the Society for Personality and Social Psychology, Inc·C L Muehlenhard, L A Kimes
Jan 29, 2005·Annals of the New York Academy of Sciences·Eva FriesMichael J Meaney
Jun 23, 2005·Child Abuse & Neglect·Desmond K RunyanElizabeth D Knight
Jun 23, 2005·Child Abuse & Neglect·Howard DubowitzMaureen M Black

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Citations

Jan 12, 2021·Development and Psychopathology·Seth D Pollak, Barbara L Wolfe
Dec 18, 2020·Journal of Neurodevelopmental Disorders·Karen E Smith, Seth D Pollak
Apr 24, 2021·Cognitive, Affective & Behavioral Neuroscience·Karen E Smith, Seth D Pollak
May 13, 2021·Journal of Neural Transmission·Ulrike U BenteleEva Unternaehrer
Jun 19, 2021·Frontiers in Human Neuroscience·Jamie L Hanson, Brendon M Nacewicz
Jul 28, 2021·Development and Psychopathology·Lucy S KingKathryn L Humphreys
Aug 12, 2021·Research on Child and Adolescent Psychopathology·Kelli L DickersonJodi A Quas
Sep 26, 2021·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Bryan V KennedySeth D Pollak
Nov 16, 2021·Psychological Medicine·Joyce ZhangRichard Meiser-Stedman

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