Jan 1, 1987

Retinal afferent and efferent connections in congenitally monophthalmic chicks

Brain, Behavior and Evolution
J Stuchbery, D Ehrlich

Abstract

The visual projections of the remaining eye of posthatch congenitally monophthalmic chicks were examined using wheat germ agglutinin-horseradish peroxidase. The morphology of the primary visual centres and their retinal projections contralateral to the injected eye were similar to those of normal chicks. The ipsilateral primary visual centres were smaller and less organized, yet all received retinal input. These ipsilateral retinal projections differ from those found in normal posthatch chicks [O'Leary et al.: Devl. Brain Res. 10: 93-109, 1983] in that they are more extensive and occupy some centres not previously reported to receive input. In the case of the ipsilateral isthmo-optic projection to the retina there was a substantial increase in the number of cells compared with normal chicks [O'Leary and Cowan: Devl. Brain Res. 12: 293-310, 1984]. A comparison of the extent of ipsilateral retinal afferents with that of normal chicks suggests that following loss of an eye two responses occur within the visual centres: in some centres there is a massive increase in the amount of ipsilateral terminals, whereas in others there is only a small increase. We propose that these responses are related to the intrinsic retinotopy within th...Continue Reading

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Mentioned in this Paper

Alpha-Peroxidase
Optic Tract Structure
Wheat Germ Agglutinin Isolectin 2
Brain
Retina
Afferent Neuron
Neurons, Efferent
Metazoa
Eye Abnormalities

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