Retinal and choroidal contribution to retinal metabolism in vivo. A study in pigs

Acta Physiologica Scandinavica
P Törnquist, A Alm


The glucose metabolism of the retina was studied in vivo, by determining glucose, oxygen and lactate a-v differences for choroidal and retinal blood in pigs at different levels of intraocular pressure. At normal intraocular pressure the choroidal a-v differences were 0.07 and 0.11 mmol/l for glucose and oxygen respectively. The corresponding figures for the retina were 0.44 and 2.15. At increased levels of intraocular pressure the choroidal and retinal glucose and choroidal oxygen a-v differences increased, thus at least partly compensating for reduced blood flow. A major part of the oxygen and glucose consumed by the retina was delivered by the choroid. The total amount of oxygen extracted from choroidal and retinal blood could only account for complete oxidation of 37% of the extracted glucose. The results obtained in determinations of lactate a-v differences indicate that part of the remaining glucose is used for anaerobic glycolysis.


Jul 1, 1979·Acta Physiologica Scandinavica·P TörnquistA Bill
Jan 17, 1970·Lancet·R A Weale
Jun 1, 1972·Journal of Medical Genetics·R B Lowry
Jun 1, 1974·Journal of Neurochemistry·K Norberg, B K Siesjö
Mar 1, 1971·The American Journal of Physiology·D L Yudilevich, N De Rose
May 1, 1970·Comparative Biochemistry and Physiology·A C Smith
Nov 1, 1965·The Journal of Physiology·C Crone
Jan 1, 1959·Pflügers Archiv : European journal of physiology·H BARTELS, H HARMS
Jul 1, 1963·The American Journal of Physiology·B E COHAN, S B COHAN
Jan 1, 1965·Acta Ophthalmologica·R L ELLIOTTP M BEIGELMAN


Feb 1, 1983·International Ophthalmology·A BillK Ujiie
Jan 1, 1990·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·A Bill, G O Sperber
Jul 1, 1989·International Ophthalmology·P Gasser
Mar 31, 2004·Experimental Eye Research·Karl-Georg SchmidtT W Mittag
Mar 14, 2003·Experimental Eye Research·Steffen HamannThomas Zeuthen
Nov 22, 2000·Brain Research. Brain Research Reviews·A Ames
Jul 7, 1999·Neuroscience·D Z GerhartL R Drewes
Mar 11, 2011·Eye·D J MordantA I McNaught
Feb 1, 1992·The Journal of General Physiology·R A Linsenmeier, R D Braun
Apr 13, 2004·Retina·Norman P BlairMichael P Blair
Oct 26, 2000·The British Journal of Ophthalmology·K G SchmidtH P Hammes
Jul 4, 2013·Investigative Ophthalmology & Visual Science·Justin WanekMahnaz Shahidi
Jun 1, 1997·American Journal of Ophthalmology·V Hessemer, K G Schmidt
Oct 24, 2015·Current Diabetes Reports·David J Ramsey, G B Arden
Mar 9, 2013·Acta Ophthalmologica·Sveinn Hakon Hardarson
Sep 1, 1983·Experimental Eye Research·E StefánssonM B Landers
Feb 1, 1983·Experimental Eye Research·A L BetzG W Goldstein
Sep 1, 1989·Experimental Eye Research·C J PournarasK Strommer
Feb 1, 1989·Diabetes/metabolism Reviews·C W Marano, F M Matschinsky
Oct 21, 2014·Clinical & Experimental Ophthalmology·Soo Khai NgRobert J Casson
Apr 26, 2015·Documenta Ophthalmologica. Advances in Ophthalmology·Michal PostWojciech Lubiński
Oct 24, 1997·Vision Research·J M HarrisonS Smith
Jul 4, 2016·Histochemistry and Cell Biology·Andreas OhlmannErnst R Tamm
Mar 1, 1997·Visual Neuroscience·M A McRipleyR A Linsenmeier
Oct 20, 2017·Anesthesia and Analgesia·Dermot J Kelly, Sinéad M Farrell
Aug 1, 2018·European Journal of Ophthalmology·Arnaud MesserlinDavid Gaucher
Oct 26, 2007·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Rhianon L PerrottRachel V North
Apr 5, 2001·American Journal of Physiology. Cell Physiology·N J PhilpL Lombardi
Dec 6, 2008·Journal of Applied Physiology·Martina M BoschKlara Landau
Jun 1, 1997·Acta Ophthalmologica Scandinavica·L Wang, A Bill
Apr 24, 2018·Journal of Ophthalmology·Yi Jing YangQing Hua Peng

Related Concepts

Blood Glucose
Glucose, (beta-D)-Isomer
Hydrogen-Ion Concentration
Physiologic Intraocular Pressure
Oxygen Consumption
Pecten Oculi

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Synthetic Genetic Array Analysis

Synthetic genetic arrays allow the systematic examination of genetic interactions. Here is the latest research focusing on synthetic genetic arrays and their analyses.

Congenital Hyperinsulinism

Congenital hyperinsulinism is caused by genetic mutations resulting in excess insulin secretion from beta cells of the pancreas. Here is the latest research.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Epigenetic Memory

Epigenetic memory refers to the heritable genetic changes that are not explained by the DNA sequence. Find the latest research on epigenetic memory here.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Femoral Neoplasms

Femoral Neoplasms are bone tumors that arise in the femur. Discover the latest research on femoral neoplasms here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.