PMID: 9646084Jul 1, 1998Paper

Retinal capillary density in patients with arterial hypertension: 2-year follow-up

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
P KutschbachM Reim

Abstract

Arterial hypertension is known to be an important risk factor for cerebral and cardiovascular disease. Previous studies have demonstrated a decrease of capillary density in the perifoveal network in tandem with decreased capillary flow velocity in patients with essential hypertension. In a prospective study we quantified the retinal microcirculation in order to evaluate the time course of changes in the perifoveal network. Thirty-three patients with essential hypertension (mean age 45 +/- 14 years) underwent video-fluorescein angiographic studies at baseline and at 2 years 28 +/- 6 months) thereafter. The angiograms were obtained with a scanning laser ophthalmoscope and were digitally recorded. By means of digital image analysis we quantified off-line the mean area of perifoveal intercapillary areas (PIA) and the mean capillary flow velocity. At baseline, the patients with hypertension showed significantly increased PIA and a significantly decreased capillary flow velocity compared with reference values. During the follow-up period the capillary flow velocity decreased further significantly, whereas the PIA showed no significant change. The continuous decrease of capillary flow velocity demonstrates a progression of altered mic...Continue Reading

Citations

Jun 8, 2012·Current Hypertension Reports·Vasiliki KatsiIoannis Kallikazaros
Nov 25, 2000·The British Journal of Ophthalmology·O ArendA Remky
Nov 27, 2002·Clinical and Experimental Hypertension : CHE·Daniele TomassoniFrancesco Amenta
Jul 18, 2008·Clinical and Experimental Hypertension : CHE·Fatih C GundoganMehmet Z Bayraktar
Nov 7, 2002·Journal of Human Hypertension·S ChatterjeeS Chattopadhya
May 31, 2002·Journal of Human Hypertension·M PacheP Kutschbach
Jan 14, 2004·The Korean Journal of Internal Medicine·Hun Ho SongKwang Hack Lee
Apr 8, 2020·Current Eye Research·Yunxia LiTimothy Q Duong
Oct 28, 2019·Journal of Clinical Monitoring and Computing·Jurate SimkieneAndrius Pranskunas
Aug 8, 2020·Investigative Ophthalmology & Visual Science·Wendy LeskovaNorman R Harris
May 20, 2021·Journal of the American Geriatrics Society·Alison G AbrahamPradeep Y Ramulu

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.

Related Papers

Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics
Sam ZeraatianMaziar Mahjoubi Fard
Current Hypertension Reports
James S Wolffsohn, Peter G Hurcomb
© 2022 Meta ULC. All rights reserved