Retinal capillary hemodynamics and VEP/pressure tolerance: evidence of retinal microcirculatory compromise in treated glaucomatous eyes

Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde
W E SponselP L Kaufman

Abstract

Measurements of retinal leukocyte velocity were made in single eyes of 6 glaucomatous adults and 9 normal subjects at each of 4 discrete levels of IOP elevation assigned according to the characteristics of prior pattern-evoked cortical potential pressure tolerance measurements. Glaucomatous eyes failed to demonstrate any stabilization in retinal leukocyte velocity at pressures above 45 mm Hg, with velocities 33% lower than normal for a comparable degree of IOP elevation (p < 0.012). Even at baseline IOP, leukocyte velocity was 27.2% slower in the treated glaucomatous eyes than in normal control eyes (p < or = 0.013), despite comparable baseline IOP levels in both groups.

Citations

Apr 4, 2008·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Niklas PlangeKay Oliver Arend
Aug 2, 2002·Progress in Retinal and Eye Research·Josef FlammerEinar Stefánsson
Oct 25, 2003·Progress in Retinal and Eye Research·Vital P CostaLuis Metzner Serra
Oct 9, 2008·Experimental Eye Research·Subha T VenkataramanJohn G Flanagan
May 30, 2003·Pharmacological Reviews·Noboru Toda, Tomio Okamura

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