Retinal detachment in retinitis pigmentosa.

BMJ Open Ophthalmology
Weng Onn ChanMahiul M K Muqit

Abstract

Retinitis pigmentosa-related retinal detachment (RPRD) is rare, and the full spectrum of retinal complications is not well defined. To describe the types of retinal detachment in patients with retinitis pigmentosa and the surgical outcomes of RPRD. This is a non-comparative, retrospective case series. An electronic database search was performed using Moorfields OpenEyes electronic health records. We identified 90 patients with RPRD between January 2000 and August 2017. Main outcome and measures are visual acuity (VA), surgical outcomes and classification of RPRD. Of the 90 patients/detachments, 61 (67.8%) were rhegmatogenous retinal detachment (RRD), 19 (21.1%) were exudative, 3 (3.3%) were tractional retinal detachment (TRD) and 7 (7.8%) had combined. 37.5% (9/24) of patients with exudative retinal detachment were treated with either cryotherapy or laser, and one patient underwent vitrectomy for vitreous haemorrhage. 56/90 patients underwent surgical intervention. Nine patients presented late and were deemed inoperable (two exudative and seven RRD). Of the RRD patients with full operative record, the primary attachment rate was 76.2% (16/21) and final reattachment rate was 85.7% (18/21) over a mean 15.4-year follow-up period. ...Continue Reading

References

Mar 1, 1978·The British Journal of Ophthalmology·P A Sieving, G A Fishman
May 1, 1974·American Journal of Ophthalmology·B R StraatsmaA L Shabo
Dec 1, 1982·Ophthalmology·S Gartner, P Henkind
Jan 1, 1996·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·E M VingoloP Onori
Aug 8, 1998·Progress in Retinal and Eye Research·A H MilamR N Fariss
Nov 25, 2000·The British Journal of Ophthalmology·P R van den BiesenD van Norren
Jan 31, 2003·Investigative Ophthalmology & Visual Science·Dana K VaughanDaniel T Organisciak
Sep 24, 2010·Investigative Ophthalmology & Visual Science·Mahiul M K MuqitPaulo E Stanga
Nov 9, 2011·Human Mutation·Kinga BujakowskaChristina Zeitz
Oct 22, 2013·Seminars in Ophthalmology·Miriam EhrenbergAnne B Fulton
Mar 18, 2015·Nature Reviews. Cardiology·Stefan JamesChristopher B Granger
Jan 1, 2018·Ophthalmology Retina·Ekta RishiTarun Sharma

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