PMID: 7536911Apr 1, 1995Paper

Retinal distortion and cotton-wool spots associated with epiretinal membrane contraction

Ophthalmology
J G Arroyo, A R Irvine

Abstract

Several articles on surgery for macular pucker have noted the presence of intraretinal white spots, presumably cotton-wool spots, associated with epiretinal membranes. It was proposed that membrane contraction and resultant nerve fiber layer distortion might lead to blockage of axoplasmic flow and thus a cotton-wool spot. To see whether the observations supported this concept, the authors studied patients with epiretinal membranes associated with intraretinal white spots involving the center of the fovea, where there are normally no retinal vessels and the only axons are in Henle fiber layer. Four patients with epiretinal membranes associated with prominent areas of intraretinal whitening involving the center of the fovea were examined before and after surgery. Observations and measurements were made from projected fundus photographs. The intraretinal white spots, which appeared preoperatively to lie in the center of the fovea, proved to have been pulled in from more peripheral retina by the epiretinal membrane. These white areas were associated with surprisingly great distortion of the inner retina. Stretching of the inner retina seemed to play a larger role in the retinal distortion than full-thickness retinal folding. The ap...Continue Reading

References

Jan 1, 1989·American Journal of Industrial Medicine·C McDonald, A McDonald
Nov 1, 1981·American Journal of Ophthalmology·R G Michels
Oct 1, 1959·American Journal of Ophthalmology·J R WOLTER

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Citations

Jul 9, 2013·The British Journal of Ophthalmology·Glenn YiuJorge G Arroyo
May 29, 2012·Ophthalmology·Mads Kofod, Morten la Cour
Aug 19, 2015·Asia-Pacific Journal of Ophthalmology·Min Kyu ShinJi Eun Lee
Oct 21, 2016·Clinical & Experimental Ophthalmology·Hessom RazaviAlex Harper
Mar 1, 1997·American Journal of Ophthalmology·E T CunninghamR N Johnson
Sep 18, 2018·Ophthalmic Surgery, Lasers & Imaging Retina·Sohee JeonWon Ki Lee
Apr 7, 2007·Journal of Pediatric Ophthalmology and Strabismus·Vikas Chadha, Andrew Barr

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