Retinal hemodynamics in early diabetic macular edema

Diabetes
Kit GuanJohn G Flanagan

Abstract

The objective of this study was to establish the baseline retinal hemodynamic characteristics of stratified groups of diabetic patients at increasing risk for the development of diabetic macular edema (DME). Group 1 had 50 control subjects, group 2 had 56 diabetic patients without clinically visible retinopathy, group 3 had 54 diabetic patients with microaneurysms and/or hard exudates within two disc diameters of the fovea in the absence of clinically manifest DME, and group 4 had 40 patients with clinically manifest DME. Retinal hemodynamics (diameter, velocity, maximum-to-minimum velocity ratio, and flow) were assessed. Intraocular pressure, blood pressure, and relevant systemic markers of diabetes control and complications were also undertaken. The maximum-to-minimum velocity ratio was elevated with increasing risk of clinically significant DME (P < 0.0001). No significant differences were found between the groups with respect to diameter, velocity, or flow. The maximum-to-minimum velocity ratio was correlated to age, duration of diabetes, blood pressure, pulse rate, intraocular pressure, and serum potassium levels. In conclusion, the maximum-to-minimum velocity ratio was significantly increased with increasing risk of devel...Continue Reading

References

Sep 19, 1992·BMJ : British Medical Journal·V PatelE Kohner
Sep 1, 1991·IEEE Transactions on Bio-medical Engineering·M T MilbockerD G Goger
Jul 1, 1986·Archives of Ophthalmology·J E GrunwaldB L Petrig
Sep 1, 1987·IEEE Transactions on Bio-medical Engineering·G T FekeF C Delori
Jan 1, 1988·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·F C DeloriJ J Weiter
Feb 1, 1983·Archives of Ophthalmology·A YoshidaJ W McMeel
May 1, 1984·Survey of Ophthalmology·F L Ferris, A Patz
Apr 1, 1994·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·O ArendM Reim
Mar 15, 2001·American Journal of Physiology. Heart and Circulatory Physiology·E PolskaL Schmetterer
Feb 5, 2002·American Journal of Hypertension·Rachel H MackeyLewis H Kuller
Dec 19, 2002·Diabetologia·M Porta, F Bandello
Apr 16, 2003·Circulation·Ronald M A HenryUNKNOWN Hoorn Study
Apr 26, 2003·The British Journal of Ophthalmology·G DimitrovaS Kitano
Aug 28, 2003·Diabetes Care·Jonathan Betz BrownKent H Summers
Feb 28, 2004·Stroke; a Journal of Cerebral Circulation·Duanping LiaoA Richey Sharrett
Aug 25, 2004·Survey of Ophthalmology·Paris G TranosCarlos E Pavesio
Aug 25, 2004·Investigative Ophthalmology & Visual Science·Tien Yin WongMaria I Schmidt
Nov 10, 2004·Archives of Ophthalmology·David R MatthewsUNKNOWN UK Prospective Diabetes Study Group
Apr 30, 2005·Diabetes Research and Clinical Practice·Osamu OgawaRyuzo Kawamori
May 10, 2005·Ophthalmology·M Cristina LeskeUNKNOWN Barbados Eye Study Group

❮ Previous
Next ❯

Citations

May 1, 2009·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Martin HammerJürgen Strobel
Nov 28, 2012·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Stefan PalkovitsLeopold Schmetterer
Feb 23, 2011·Journal of Medical Systems·U Rajendra AcharyaKwan-Hoong Ng
Jan 12, 2010·Retina·Zvia Burgansky-EliashAdiel Barak
Sep 1, 2011·Retina·Zvia Burgansky-EliashArdon Rubinstein
Oct 20, 2006·The British Journal of Ophthalmology·Andrew J Morgan, Sarah L Hosking
Nov 21, 2007·Annals of Nutrition & Metabolism·José E GalganiErik O Díaz
Feb 10, 2011·Annals of Nutrition & Metabolism·Sergio Muntoni, Sandro Muntoni
Jun 27, 2009·Journal of Pediatric Endocrinology & Metabolism : JPEM·Natasha LeibelSharon E Oberfield
May 1, 2006·Expert Review of Clinical Immunology·Sally E ThomsonStephen M Twigg
Jun 22, 2013·Expert Opinion on Medical Diagnostics·Bruce A BerkowitzRobin Roberts
Feb 6, 2013·Diabetes Research and Clinical Practice·Thuan M Diep, Irena Tsui
Feb 4, 2009·Ophthalmology·Gabriella TikellisTien Y Wong
May 2, 2008·Progress in Retinal and Eye Research·Constantin J PournarasEinar Stefansson
Dec 2, 2006·Microvascular Research·Patricia A Rose, Chris Hudson
Oct 1, 2011·Acta Ophthalmologica·Behrooz AziziChris Hudson
May 23, 2013·IEEE Transactions on Image Processing : a Publication of the IEEE Signal Processing Society·Behdad DashtbozorgAurélio Campilho
Jan 15, 2015·Physiological Measurement·Tsukasa IkemuraNaoyuki Hayashi
Jan 29, 2019·Acta Ophthalmologica·Faryan TayyariChristopher Hudson
May 31, 2017·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Ebony LiuKathryn Burdon
Oct 18, 2007·Current Opinion in Endocrinology, Diabetes, and Obesity

❮ Previous
Next ❯

Related Concepts

Related Feeds

Biomarkers for Diabetes

This feed focuses on the latest research on biomarkers used for monitoring disease progression in diabetes.

American Diabetes Association Journals

Discover the latest diabetes research published by the journals from the American Diabetes Association.