Retinal nerve fiber layer assessment by scanning laser polarimetry and standardized photography

American Journal of Ophthalmology
A G NiessenE L Greve

Abstract

To determine whether, in a clinical setting, scanning laser polarimetry and retinal nerve fiber layer photography provide equivalent information on the retinal nerve fiber layer. We prospectively studied 60 patients with glaucoma or ocular hypertension and 24 healthy subjects. With scanning laser polarimetry, an estimate of the cross section of the retinal nerve fiber layer was obtained. By using a photographic reference set, we quantified photographs of the retinal nerve fiber layer. Visual fields were used to relate the results of both methods to functional damage. The scanning laser polarimetry measurements yielded reproducible cross-section values (coefficient of variation, 6.6%). Comparison of cross-section values and photograph scores gave Pearson correlation coefficients smaller than r = .4 (P < .01), improving to a maximum of r = .53 after compensation for offset. When cross-section values were compared to the mean deviation of the visual field, the Spearman correlation coefficients varied from an r of -.34 to -.53 (P < .01). Correction for offset resulted in an r of -.54 to -.65. When photograph scores and mean deviation of the visual field were compared, the Spearman correlation coefficients varied from an r of -.65 t...Continue Reading

References

Nov 1, 1995·American Journal of Ophthalmology·A G NiessenP M Bossuyt

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Citations

Nov 5, 1997·American Journal of Ophthalmology·J Caprioli
Jan 29, 2002·American Journal of Ophthalmology·Mohamed A E SolimanMarc D De Smet
Apr 17, 2002·Journal of Cataract and Refractive Surgery·Michael S KookKyung- rhee Kim
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Aug 6, 1999·European Journal of Ophthalmology·S KogureS Tsukahara
Nov 7, 2008·European Journal of Ophthalmology·D S GrewalV Rihani

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