Retinal photoablation with the Erbium:YAG laser. Initial experimental results for traction-free removal of tissue

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
H HoeraufH Laqua

Abstract

To investigate the potential of an Er:YAG laser for precise and traction-free removal of retinal layers in vitro. Retinal ablation in porcine retinal explants was performed using a free running Er:YAG laser focused either into a low-OH quartz fiber or a sapphire fiber. The explants were treated under air or perfluorodecaline (PFD). The ablation depth was evaluated by optical coherence tomography (OCT) and histology sections. A radiant exposure of 5.0 J/cm(2) under air and PFD resulted in complete transsection of the neurosensory retina. Between 3.5 and 2.0 J/cm(2) the ablation depth and the defect patterns varied markedly and adjacent thermal zones areas were seen. Below 2.0 J/cm(2) no defects could be created in air, whereas under PFD the ablation extended into the ganglion cell layer. Ablations using a sapphire fiber and 2.0 J/cm(2) showed a significantly higher reproducibility of ablation depth, and homogeneous defect patterns limited to the nerve fiber layer could be produced without thermal damage. The Er:YAG laser system with a low-OH quartz fiber allowed ablation of inner retinal layers in vitro, but revealed a variable ablation depth and low reproducibility.However, a sapphire fiber showed markedly improved results. The...Continue Reading

Citations

Nov 12, 2005·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·H P N SchollF G Holz
Oct 6, 2005·Retina·Siegfried G PriglingerAnselm Kampik
Jun 28, 2012·Journal of Biomedical Optics·Thomas C HutchensNathaniel M Fried
Oct 16, 2008·Minimally Invasive Therapy & Allied Technologies : MITAT : Official Journal of the Society for Minimally Invasive Therapy·K F MackB Schwab
Apr 10, 2008·Current Eye Research·Matthias HildKarsten König

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