PMID: 3745964May 1, 1986Paper

Retinal pigment epithelium function in alopecia areata

The Journal of Investigative Dermatology
Antonella TostiE Maccolini

Abstract

Electroretinography (ERG) and electro-oculography (EOG) were performed in 98 patients affected by alopecia areata (AA) free from ophthalmologic disorders, and in 40 healthy subjects, in order to evaluate whether or not the retinal pigment epithelium of AA patients shows bioelectrical changes. ERG was normal. EOG, on the contrary, showed a significantly depressed mean value in the AA patient group. Furthermore, depressed EOG occurred more frequently in patients affected by alopecia totalis or universalis as compared with multiple patchy alopecia. These findings prompt the authors to believe that the melanocytes may play a prominent part in the pathogenesis of AA.

Citations

Mar 4, 2000·Eye·S M RecuperoS Calvieri
Apr 12, 2016·International Journal of Dermatology·Oktay EsmerAyse S Karadag
Apr 20, 2012·The New England Journal of Medicine·Amos GilharRalf Paus
Jul 7, 2015·International Journal of Dermatology·Can ErginCanan Gürdal
Nov 9, 2000·The British Journal of Dermatology·N Raison-PeyronC Hamel
Nov 2, 2013·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·V von Felbert, H F Merk
Apr 23, 2009·The Journal of Dermatology·Deepika PandhiGopal Das
Dec 3, 2014·Immunologic Research·Francisco Assis De AndradeJuan Ferrando

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