Retinal pigmentary changes in chronic uveitis mimicking retinitis pigmentosa

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
D Damla SevgiLucia Sobrin

Abstract

To present retinal pigmentary changes mimicking retinitis pigmentosa (RP) as a finding of advanced uveitis. We retrospectively reviewed charts of patients without a family history of inherited retinal degenerations who presented with retinal pigment changes and signs of past or present intraocular inflammation. Comprehensive eye examination including best-corrected visual acuity, slit-lamp examination and dilated fundus examination was performed on all patients in addition to color fundus photography, optical coherence tomography, fluorescein angiography (FA), and full-field electroretinogram testing. We identified five patients with ages ranging from 33 to 66 years, who presented with RP-like retinal pigmentary changes which were eventually attributed to longstanding uveitis. The changes were bilateral in three cases and unilateral in two cases. Four of five cases presented with active inflammation, and the remaining case showed evidence of active intraocular inflammation during follow-up. This study highlights the overlapping features of advanced uveitis and RP including the extensive pigmentary changes. Careful review of possible past uveitis history, detailed examination of signs of past or present inflammation and ancillar...Continue Reading

References

Mar 15, 1986·American Journal of Ophthalmology·D A Newsome
May 20, 1999·American Journal of Ophthalmology·J R HeckenlivelyN Aptsiauri
Oct 13, 2006·Orphanet Journal of Rare Diseases·Christian Hamel
Dec 4, 2013·Investigative Ophthalmology & Visual Science·Paul L Kaufman
Jan 24, 2014·Clinical Ophthalmology·Marilita M MoschosChristos Kalogeropoulos
Feb 12, 2014·BMJ Case Reports·Julia M WellerAnselm G Juenemann
Nov 21, 2014·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Mark B ConsugarEric A Pierce
Feb 14, 2015·American Journal of Ophthalmology·Yusuke MurakamiTatsuro Ishibashi
Apr 7, 2016·Journal of Ophthalmic & Vision Research·Pinar Cakar OzdalIlknur Tugal-Tutkun

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Citations

Sep 1, 2019·Stem Cell Research & Therapy·Na LiRuihua Wei

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