Retinal target cells of the centrifugal projection from the isthmo-optic nucleus

The Journal of Comparative Neurology
H UchiyamaHiroshi Ohno

Abstract

Although the avian retina has long been known to receive projection from a midbrain nucleus, the isthmo-optic nucleus (ION), the output of its target cells has remained obscure. We labeled the isthmo-optic (IO) terminals in the Japanese quail retina, by using anterograde transport of fluorescent tracer injected into the ION, and then labeled target cells for these terminals by means of intracellular tracer injection under direct microscopic observation. Somata of the IO target cells (IOTCs) lie in the innermost zone of the inner nuclear layer of the ventral half of the retina and have no dendrites but an axon. The axons run in the inner plexiform layer (IPL) for up to 6 mm and terminate densely in a round or elliptical terminal field, about 90-290 microm in diameter, of the outermost zone of the IPL. Longer axons (> 2 mm) extend dorsally, but shorter ones (< 1 mm) project ventrally or horizontally, so the terminals are distributed widely in both dorsal and ventral halves of the retina. The IOTCs cannot be classified into any of the five conventional major classes of retinal cells, including amacrine cells, and are thought to be "slave" neurons whose output is controlled by the neurons in the brain. Topographic separation betwee...Continue Reading

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Citations

Feb 3, 2009·Experimental Brain Research·Hiroshi Ohno, Hiroyuki Uchiyama
Feb 14, 2006·Visual Neuroscience·H Uchiyama, W K Stell
Mar 20, 2009·Visual Neuroscience·Cynthia WellerMartin Wilson
May 15, 2009·Visual Neuroscience·S H LindstromMartin Wilson
Jul 24, 2010·Visual Neuroscience·Sarah H LindstromMartin Wilson
Apr 29, 2011·Visual Neuroscience·Martin Wilson, Sarah H Lindstrom
May 11, 2011·Visual Neuroscience·Martin WilsonDavid I Vaney
May 23, 2012·Behavioural Brain Research·Hiroyuki UchiyamaRyuki Kodama
Mar 4, 2017·The Journal of Comparative Neurology·Quirin KrabichlerHarald Luksch
May 31, 2007·The Journal of Comparative Neurology·Andy J FischerGhezal Omar
Mar 31, 2006·The Journal of Comparative Neurology·Andy J FischerNathaniel A Walton

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