Retinal vascular changes in preterm infants: heart and lung diseases and plus disease

Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
Andrea Elizabeth Arriola-LopezMaria Ana Martinez-Castellanos

Abstract

To report the retinal vascular features of preterm infants with congenital heart disease (CHD), lung disease (pulmonary hypertension [PH] and bronchopulmonary dysplasia [BPD]), and ROP with plus disease to determine whether these disease entities are distinguishable on the basis of retinal vessel morphology. The medical records of preterm infants with CHD, lung disease, and ROP with plus disease were reviewed retrospectively. Qualitative vascular findings were validated using computer-based software to analyze 25 representative images, each corresponding to one infant's eye. The images were organized into five groups, based on clinical information. Vessel diameter (d) and tortuosity index (TI) were measured. A total of 106 infants (mean gestational age, 30.5 ± 2.22 weeks) were initially included. Ophthalmologic evaluation of preterm infants with CHD and lung diseases showed vascular tortuosity without vasodilation at the posterior pole as well as in the periphery. Quantitative analysis showed that venular diameter was significantly increased in the plus disease group (P = 0.0022) compared to other groups. There was significantly less tortuosity in both arterioles and venules in BPD (P < 0.001, P = 0.0453) compared with plus gro...Continue Reading

References

Aug 1, 2002·IEEE Transactions on Bio-medical Engineering·M Elena Martinez-PerezKim H Parker
Dec 9, 2003·The British Journal of Ophthalmology·C SwansonA R Fielder
Dec 10, 2003·Archives of Ophthalmology·UNKNOWN Early Treatment For Retinopathy Of Prematurity Cooperative Group
Jun 9, 2004·Eye·A M MansourH I Salti
Nov 24, 2005·Investigative Ophthalmology & Visual Science·Rony GelmanAnne B Fulton
Jan 6, 2007·Medical Image Analysis·M Elena Martinez-PerezKim H Parker
Jul 9, 2013·Investigative Ophthalmology & Visual Science·Victor H GuaiquilCarl P Blobel
Oct 23, 2013·Hypertension·Megan R SutherlandAnne Monique Nuyt
Mar 29, 2014·Pediatric Allergy, Immunology, and Pulmonology·Christopher D BakerPeter M Mourani
Apr 12, 2016·Frontiers in Pediatrics·Lidys RiveraPatricia Silveyra

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Citations

Jan 19, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Maria A Martínez-CastellanosLuis A Gonzalez-Gonzalez

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