Retinoic acid signaling in vascular development

Genesis : the Journal of Genetics and Development
Brad PawlikowskiJulie A Siegenthaler

Abstract

Formation of the vasculature is an essential developmental process, delivering oxygen and nutrients to support cellular processes needed for tissue growth and maturation. Retinoic acid (RA) and its downstream signaling pathway is vital for normal pre- and post-natal development, playing key roles in the specification and formation of many organs and tissues. Here, we review the role of RA in blood and lymph vascular development, beginning with embryonic yolk sac vasculogenesis and remodeling and discussing RA's organ-specific roles in angiogenesis and vessel maturation. In particular, we highlight the multi-faceted role of RA signaling in CNS vascular development and acquisition of blood-brain barrier properties.

References

Nov 1, 1988·Microvascular Research·S E ConnollyP A D'Amore
Nov 30, 1989·Cancer Letters·T OikawaT Iwaguchi
Apr 15, 1994·The Biochemical Journal·J Urbach, R R Rando
Jan 1, 1993·Advances in Experimental Medicine and Biology·P McCaffery, U C Dräger
Nov 1, 1995·Developmental Dynamics : an Official Publication of the American Association of Anatomists·G BreierW Risau
Aug 6, 1999·Developmental Biology·L MiquerolA Nagy
Mar 8, 2000·Developmental Dynamics : an Official Publication of the American Association of Anatomists·S A Gebb, J M Shannon
Aug 2, 2000·American Journal of Respiratory Cell and Molecular Biology·S McGowanJ M Snyder
Nov 7, 2000·Developmental Dynamics : an Official Publication of the American Association of Anatomists·A M HealyW V Cardoso
Feb 13, 2001·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Y S NgP A D'Amore
Jan 5, 2002·The Journal of Biological Chemistry·Omolara O OgunsholaLaura R Ment
Jun 5, 2003·Proceedings of the National Academy of Sciences of the United States of America·Felix A MicGregg Duester
Oct 31, 2003·Molecular Aspects of Medicine·H K Biesalski, D Nohr
Nov 19, 2003·Proceedings of the National Academy of Sciences of the United States of America·Valérie DupéNorbert B Ghyselinck
Nov 25, 2003·Development·Lihua LaiKaren K Hirschi
Aug 6, 2004·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Malcolm Maden, Matthew Hind
Sep 6, 2005·American Journal of Respiratory Cell and Molecular Biology·Su Jin ChoMichael J Acarregui
Oct 7, 2005·Development·Nicolas MattNorbert B Ghyselinck
Dec 15, 2005·Proceedings of the National Academy of Sciences of the United States of America·Esther MerkiPilar Ruiz-Lozano
Dec 27, 2005·The Journal of Biological Chemistry·Horace M DeLisserRashmin C Savani
Apr 25, 2006·Nature Reviews. Molecular Cell Biology·Anna-Karin OlssonLena Claesson-Welsh
Nov 15, 2006·Molecular and Cellular Endocrinology·Sebastian HoffmannAndreas Zielke
Jan 11, 2007·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Vanessa RibesPascal Dollé
Feb 27, 2007·Angiogenesis·Marcus Fruttiger
May 25, 2007·Nature Reviews. Molecular Cell Biology·Ralf H Adams, Kari Alitalo
Oct 29, 2008·The Journal of Cell Biology·Stefan LiebnerElisabetta Dejana
Jan 9, 2009·Proceedings of the National Academy of Sciences of the United States of America·Richard DanemanBen A Barres
Apr 22, 2009·Nuclear Receptor Signaling·Manuel MarkPierre Chambon
Oct 21, 2009·Proceedings of the National Academy of Sciences of the United States of America·Magali Saint-GeniezPatricia A D'Amore
Oct 21, 2009·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Hongbin LiuSteven A Fisher

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Citations

May 9, 2019·Genesis : the Journal of Genetics and Development·Suya Wang, Alexander R Moise
Jan 23, 2020·Biomolecules·Hugo Fernandes-SilvaRute S Moura
Apr 4, 2021·International Journal of Molecular Sciences·Ho-Wei HsuJong-Hau Hsu
Sep 14, 2021·Toxicological Sciences : an Official Journal of the Society of Toxicology·Lauren Kirkwood-JohnsonYusuke Marikawa

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