Retinopathy of prematurity: New developments bring concern and hope

Journal of Paediatrics and Child Health
Brian A Darlow

Abstract

Blindness from retinopathy of prematurity (ROP) in Australian and New Zealand is an uncommon event although 3% of <31 weeks gestation infants receive treatment for the disease. New world-wide estimates of the incidence of blindness from ROP are much higher than previously at 20 000 children annually. The impact of severe ROP can be reduced through good evidence-based care of very preterm infants and careful organisation of eye examinations and follow-up services. Recent oxygen saturation targeting trial results might mean the adoption of higher targets than formerly in very preterm infants and will require vigilance to ensure all eligible infants are examined appropriately. A true screening examination for acute ROP might involve non-opthalmologists obtaining photographic retinal images and remote reading of these. Although treatment with laser gives good outcomes, there is interest in intravitreal anti-vascular endothelial factor agents, but issues concerning the systemic safety and retinal results of such treatment are unresolved.

References

Feb 1, 1990·Australian and New Zealand Journal of Ophthalmology·B A Darlow, R S Clemett
Sep 1, 1988·Archives of Disease in Childhood·B A Darlow
Oct 27, 1973·Lancet·K W Cross
Mar 27, 2002·Eye·L HainesUNKNOWN Royal College of Paediatrics and Child Health, the Royal College of Ophthalmologists and British Association of Perinatal Me
Aug 10, 2002·American Journal of Physiology. Lung Cellular and Molecular Physiology·Timothy D Le CrasSteven H Abman
Aug 6, 2004·Endocrine Reviews·Napoleone Ferrara
Apr 19, 2005·Developmental Medicine and Child Neurology·Ashima MadanWilliam V Good
Nov 3, 2006·Pediatrics·Nathaniel R PayneUNKNOWN Breathsavers Group, Vermont Oxford Network Neonatal Intensive Care Quality Improvement Collaborative
Jan 26, 2007·Archives of Disease in Childhood. Fetal and Neonatal Edition·D A ToddUNKNOWN NICUS Group
Aug 21, 2007·Seminars in Fetal & Neonatal Medicine·Anna R O'Connor, Alistair R Fielder
Mar 6, 2008·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Shigeru HondaAkira Negi
Oct 28, 2008·The British Journal of Ophthalmology·Jonathan E Sears
Aug 8, 2009·American Journal of Ophthalmology·Jonathan A MicieliAndrew F Smith
May 18, 2010·The New England Journal of Medicine·UNKNOWN SUPPORT Study Group of the Eunice Kennedy Shriver NICHD Neonatal Research NetworkRosemary D Higgins
Sep 24, 2010·The New England Journal of Medicine·William O Tarnow-MordiLex Doyle
Nov 3, 2010·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Sun Young JangSung Jin Lee
Jan 18, 2011·BMC Pediatrics·Lisa M AskieUNKNOWN NeOProM Collaborative Group
Feb 16, 2011·Archives of Ophthalmology·Graham E QuinnUNKNOWN Early Treatment for Retinopathy of Prematurity Cooperative Group
Feb 18, 2011·The New England Journal of Medicine·Helen A Mintz-HittnerUNKNOWN BEAT-ROP Cooperative Group
Mar 8, 2011·Archives of Disease in Childhood. Fetal and Neonatal Edition·Ewen D JohnstonBen J Stenson
Aug 23, 2011·Acta Paediatrica·Anna-Lena Hård, Ann Hellström
Jan 3, 2012·Archives of Disease in Childhood. Fetal and Neonatal Edition·Brian A DarlowGraham E Quinn
Apr 12, 2012·Archives of Ophthalmology·Jennifer HuRashmi Kapur
May 29, 2012·The Journal of Pediatrics·Lisa Charo BainHenry C Lee
Jun 21, 2012·Clinical & Experimental Ophthalmology·David J GunnGlen A Gole
Dec 28, 2012·The New England Journal of Medicine·Yvonne E VaucherUNKNOWN SUPPORT Study Group of the Eunice Kennedy Shriver NICHD Neonatal Research Network
Dec 28, 2012·The New England Journal of Medicine·M Elizabeth Hartnett, John S Penn
Feb 13, 2013·Current Opinion in Pediatrics·Lisa M Askie
Apr 24, 2013·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Shaun IttiaraSteven J Lichtenstein
May 7, 2013·The New England Journal of Medicine·Ben J StensonPeter Brocklehurst
May 7, 2013·The New England Journal of Medicine·Richard A Polin, David Bateman
May 7, 2013·JAMA : the Journal of the American Medical Association·Barbara SchmidtUNKNOWN Canadian Oxygen Trial (COT) Group
May 7, 2013·JAMA : the Journal of the American Medical Association·Eduardo Bancalari, Nelson Claure
May 31, 2013·Clinics in Perinatology·Lois E SmithAnn Hellström
May 31, 2013·Clinics in Perinatology·Brian W Fleck, Ben J Stenson
May 31, 2013·Clinics in Perinatology·Clare M WilsonAlistair R Fielder
May 31, 2013·Clinics in Perinatology·David K Wallace, Katherine Y Wu
May 31, 2013·Clinics in Perinatology·Gerd Holmström, Eva Larsson
May 31, 2013·Clinics in Perinatology·Graham E QuinnPeiquan Zhao
May 31, 2013·Clinics in Perinatology·Graham E Quinn, Alistair R Fielder

❮ Previous
Next ❯

Citations

Nov 14, 2015·Journal of Korean Medical Science·Jong Hee HwangEllen Ai-Rhan Kim
Jul 18, 2019·Clinical & Experimental Ophthalmology·Samantha K SimkinShuan Dai

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.