Retinopathy predicts coronary heart disease events in NIDDM patients

Diabetes Care
H MiettinenMarkku Laakso

Abstract

Proliferative retinopathy has been shown to be associated with increased all-cause mortality in diabetic patients. We assessed the relationship between the different degrees of retinopathic changes at baseline and serious coronary heart disease (CHD) events (CHD death or nonfatal myocardial infarction) in a prospective population-based study of NIDDM patients. Our study is based on the 7-year follow-up cohort of 1,059 NIDDM patients in east and west Finland. Classification of retinopathic changes was based on clinical examination of fundi, and the findings were classified to three categories according to the status of the worse eye: no retinopathic changes, background retinopathy, and proliferative retinopathy. During the 7-year follow-up, 255 (24%) patients developed serious CHD event. In patients with proliferative retinopathy at baseline, the risk of CHD events during the follow-up was statistically significantly higher compared with patients without retinopathic changes (odds ratio [OR] 2.31, 95% CI 1.21-4.40). The association between proliferative retinopathy and CHD events remained significant when other cardiovascular risk factors were controlled for. Proliferative retinopathy in NIDDM patients was associated with CHD ev...Continue Reading

Citations

Nov 5, 1998·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·M K RutterS M Marshall
Oct 21, 2006·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Takayuki OhnoShinichi Takamoto
Sep 5, 2003·Journal of Diabetes and Its Complications·Ferran Rius RiuAnna Sanmartí Sala
Mar 29, 2002·Diabetic Medicine : a Journal of the British Diabetic Association·H M ColhounUNKNOWN Collaborative AtoRvastatin Diabetes Study (CARDS)
Jun 1, 2012·BMC Ophthalmology·Bao-Anh Nguyen-KhoaJudith K Jones
Apr 3, 2001·Coronary Artery Disease·J D Rutherford
Dec 3, 2014·BMJ Open Diabetes Research & Care·Natalie A BelloScott D Solomon
Apr 30, 2013·Primary Care Diabetes·Justin B Echouffo-Tcheugui, Andre P Kengne
May 3, 2011·Revista española de cardiología·Gerald Liew, Jie Jin Wang
Dec 7, 2010·Diabetes Research and Clinical Practice·Jang-Won SonHyuk-Sang Kwon
Sep 25, 2015·Circulation Journal : Official Journal of the Japanese Circulation Society·Michio ShimabukuroUNKNOWN Fukuoka diabetologists group
Jan 29, 2008·The Annals of Thoracic Surgery·Takayuki OhnoNoboru Motomura
Feb 6, 2008·Progress in Retinal and Eye Research·Ning Cheung, Tien Y Wong
Feb 20, 2007·The American Journal of Cardiology·LaDale St Clair, Christie M Ballantyne
Jul 30, 2004·Clinical & Experimental Ophthalmology·Brendan J VotePhilip J Polkinghorne
Jul 4, 2009·Diabetic Medicine : a Journal of the British Diabetic Association·J ChanP Chow
Nov 25, 2003·BJU International·Y KawanishiH Taguchi
Jan 18, 2008·Diabetic Medicine : a Journal of the British Diabetic Association·G TargherG Arcaro
Mar 30, 2007·Journal of Interventional Cardiology·Takayuki OhnoRyozo Nagai
Nov 22, 2008·European Journal of Clinical Investigation·M T MaleckiJ Sieradzki
May 12, 2009·The American Journal of Cardiology·José A Gimeno-OrnaBeatriz Boned-Juliani
Apr 14, 2016·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Vivian Yawei GuoBenny Chung-Ying Zee
Apr 19, 2008·Journal of the American College of Cardiology·Ning CheungUNKNOWN ARIC (Atherosclerosis Risk In Communities) Study Investigators
May 28, 2005·Diabetes Care·Manon V van HeckeUNKNOWN EURODIAB prospective complications study
May 6, 2011·Diabetes Care·Markku Laakso
Aug 22, 2012·Diabetes & Vascular Disease Research : Official Journal of the International Society of Diabetes and Vascular Disease·Jian RongJing Chen
Mar 15, 2018·Indian Journal of Endocrinology and Metabolism·Kiran ShahSundaram Natarajan
Nov 6, 2020·BMC Cardiovascular Disorders·Xiao-Hong XuAi-Qiang Dong

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