Retracted: Influence of volume replacement with different HES-solutions on microcirculatory blood flow in cardiac surgery.

Acta Anaesthesiologica Scandinavica
J BoldtG Hempelmann

Abstract

A variety of hydroxyethyl starch HES preparations with different molecular weight average (Mw) and molar substitution (MS) is available for volume replacement during acute normovolemic haemodilution (ANH). Particularly with regard to microcirculation, the ideal solution for volume therapy has not been found. The influence of four different HES preparations on macro- and microcirculation was investigated in 40 patients scheduled for elective aorto-coronary bypass grafting and undergoing ANH (preoperative withdrawn blood: 10 ml.kg-1): 1) 6% HES with Mw of 450,000 dalton and MS of 0.7; 2) 6% HES with Mw of 200,000 dalton and MS of 0.5; 3) 6% HES with Mw of 200,000 dalton and MS of 0.62; 4) 6% HES with Mw of 40,000 dalton and MS of 0.5. A 5th group without ANH served as a control (10 patients in each group). In addition to systemic haemodynamics and various laboratory parameters, skin capillary blood flow was measured by laser Doppler flowmetry. Laser Doppler flow (LDF) was monitored simultaneously at the patient's forehead and forearm. Changes in systemic haemodynamics were similar in all ANH-patients. Systemic vascular resistance (SVR) was lowest after infusion of HES 200/0.5. The most pronounced increase in plasma viscosity was ...Continue Reading

References

Sep 1, 1977·The Journal of Investigative Dermatology·G A Holloway, D W Watkins
May 1, 1987·Clinical Physics and Physiological Measurement : an Official Journal of the Hospital Physicists' Association, Deutsche Gesellschaft Für Medizinische Physik and the European Federation of Organisations for Medical Physics·P I Allen, M Goldman
Aug 1, 1987·Critical Care Medicine·K WaxmanJ Hyatt
Jan 1, 1988·Scandinavian Journal of Thoracic and Cardiovascular Surgery·N al-KhajaG William-Olsson
Jul 1, 1988·Medical & Biological Engineering & Computing·M NitzanV C Roberts
Jan 1, 1985·Scandinavian Journal of Thoracic and Cardiovascular Surgery·T HirayamaG William-Olsson
Jul 1, 1985·Journal of Biomedical Engineering·D BoggettP Rolfe
Jul 1, 1984·Medical & Biological Engineering & Computing·G E Nilsson
Nov 1, 1983·The Journal of Investigative Dermatology·E TurR H Guy
Jan 1, 1983·Clinical and Experimental Dermatology·G Frentz, U Møller
Jan 1, 1981·Cleveland Clinic Quarterly·E Lowenstein

❮ Previous
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Citations

Dec 6, 2003·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Katrin LangDietmar Nagel
Mar 3, 2011·European Journal of Clinical Pharmacology·Xue-Yin ShiHu Liu
Oct 19, 2010·Journal of Anesthesia·Tomi T NiemiMichiaki Yamakage
Jan 16, 2004·Critical Care Medicine·Aryeh Shander, Aryeth Shander
Jul 1, 1995·Acta Anaesthesiologica Scandinavica·P KjellgrenF Sjöberg
Sep 17, 2003·Critical Care : the Official Journal of the Critical Care Forum·Joseph Varon, Paul E Marik
Apr 20, 2004·Wiener klinische Wochenschrift·Joachim Boldt
Jul 1, 1997·Artificial Cells, Blood Substitutes, and Immobilization Biotechnology·T W Chung, J F Wang
May 5, 1999·Artificial Cells, Blood Substitutes, and Immobilization Biotechnology·T W ChungC I Wu
Feb 22, 2012·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·A StolzingS Sethe
Jul 14, 2000·Chest·J Varon, P E Marik
Aug 6, 2009·Best Practice & Research. Clinical Anaesthesiology·Christian ErtmerMartin Westphal
Nov 4, 2006·Transplant International : Official Journal of the European Society for Organ Transplantation·Peter Schnuelle, Fokko Johannes van der Woude
Jan 6, 2000·Journal of Cardiothoracic and Vascular Anesthesia·J Boldt
Oct 27, 2009·The Annals of Thoracic Surgery·Daniel De BackerJean-Louis Vincent
May 15, 2012·The Journal of Thoracic and Cardiovascular Surgery·Roberta J NavickisMahlon M Wilkes
Aug 2, 2000·Critical Care Medicine·P E Marik, J Iglesias

❮ Previous
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