Retraining attention in MS

Journal of the Neurological Sciences
Iris-Katharina Penner, L Kappos

Abstract

Cognitive decline is frequently observed in multiple sclerosis (MS) and has a major impact on quality of life. Therefore it would be important to offer therapeutic strategies to the patients. In the past, several studies were conducted on pharmacological or cognitive treatment. However, there is currently no specific treatment for cognitive decline and the studies published so far report heterogeneous results. The present paper focuses on the cognitive treatment strategies by reviewing and discussing the few studies that have been carried out in this area. In addition, results of a recently completed fMRI study on the visualization of cognitive training effects will be reported. This review clearly points out that further research in this area is needed to clarify the effects of cognitive intervention. Larger sample sizes and standardized neuropsychological outcome measures as well as standardized training tools are required to allow for comparisons between different studies and to improve our understanding of cognitive decline and the processes of cognitive recovery in MS.

References

Jun 1, 1984·Archives of Neurology·S M RaoD Lloyd
Sep 1, 1980·Archives of Neurology·J M PeyserS B Filskov
Dec 1, 1993·Acta Neurologica Scandinavica·A JønssonE Byskov-Ottosen
May 12, 1998·Journal of Neurology, Neurosurgery, and Psychiatry·A M PlohmannJ Lechner-Scott
Dec 5, 1998·Multiple Sclerosis : Clinical and Laboratory Research·R H PaulK Hames
Jun 26, 2001·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·M Filippi
Jan 11, 2002·Journal of Neurology, Neurosurgery, and Psychiatry·N B LincolnE D Playford
Sep 11, 2002·Neurology·J A CohenUNKNOWN IMPACT Investigators
Jul 9, 2004·Journal of the Neurological Sciences·Alessandra SolariUNKNOWN CRIMS Trial

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Citations

May 16, 2007·Journal of Neurology·Alexander WinkelmannUwe K Zettl
Mar 18, 2010·International Review of Psychiatry·Lambros MessinisPanagiotis Papathanasopoulos
Aug 21, 2013·Multiple Sclerosis : Clinical and Laboratory Research·M P AmatoM Trojano
May 30, 2017·Neuropsychological Rehabilitation·Heather BeckerWenhui Zhang
Aug 31, 2019·Multiple Sclerosis : Clinical and Laboratory Research·Luca Prosperini, Massimiliano Di Filippo

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