PMID: 7546799Jan 1, 1995Paper

Retransplantation of the lung. A single center experience

European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery
H J SchäfersH G Borst

Abstract

While lung retransplantation remains the only therapeutic option in early or late graft failure, its value is viewed controversially. Of 134 patients undergoing pulmonary transplantation in our institution, 13 patients underwent 14 redos following heart-lung transplantation (n = 3), bilateral lung transplantation (n = 5), and unilateral lung transplantation (n = 5). Indications for retransplantation were acute graft failure (n = 2), persistent graft dysfunction (n = 3), airway complications (n = 2), and chronic graft failure (n = 7). Prior to retransplantation, six patients had been in stable respiratory failure, the remaining eight patients were on mechanical ventilation or extracorporeal membrane oxygenation (n = 2). Four patients died, 19, 43, 142, and 683 days following retransplantation due to pneumonia (n = 2), early onset of obliterative bronchiolitis (n = 1), and pulmonary embolism (n = 1). There was no correlation between mortality and intubation prior to re-operating, timing of operation, donor cytomegalovirus (CMV) status, or type of operation. Postoperative need for intensive care treatment was prolonged in patients undergoing acute retransplantation (P < 0.05). Actuarial 1- and 2-year survival rates were calculated...Continue Reading

Citations

Aug 6, 1998·The Annals of Thoracic Surgery·C B HuddlestonG B Mallory
Aug 26, 1998·Seminars in Thoracic and Cardiovascular Surgery·R J Novick, L Stitt
Aug 30, 2014·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Gyoergy LangWalter Klepetko
Apr 23, 2011·Clinics in Chest Medicine·Steven M Kawut
Nov 1, 1995·The Journal of Thoracic and Cardiovascular Surgery·R J NovickG A Patterson
Oct 8, 2005·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Yaron ShargallUNKNOWN ISHLT Working Group on Primary Lung Graft Dysfunction
May 6, 2015·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·S E VerledenA Haverich
Dec 1, 1996·The Journal of Thoracic and Cardiovascular Surgery·R J NovickG A Patterson
May 14, 2018·Clinical Transplantation·Kieran HalloranLianne G Singer
Apr 12, 2005·Drugs·Andrew I R ScottSusan Stewart
Dec 3, 2014·The Annals of Thoracic Surgery·Asishana A OshoMatthew G Hartwig

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