Retro-mode imaging and fundus autofluorescence with scanning laser ophthalmoscope of retinal dystrophies.

BMC Ophthalmology
Battaglia Parodi MaurizioBandello Francesco

Abstract

Retinal dystrophies display a considerably wide range of phenotypic variability, which can make diagnosis and clinical staging difficult. The aim of the study is to analyze the contribution of retro-mode imaging (RMI) and fundus autofluorescence (FAF) to the characterization of retinal dystrophies. Eighteen consecutive patients affected by retinal dystrophies underwent a complete ophthalmological examination, including best corrected visual acuity with ETDRS charts, blue-light fundus autofluorescence, (BL-FAF), near-infrared fundus autofluorescence (NIR-FAF), and RMI. The primary outcome was the identification of abnormal patterns on RMI. The secondary outcome was the correlation with the findings on BL-FAF and NIR-FAF. Overall, the main feature of RMI is represented by a pseudo-3D pattern of all the lesions at the posterior pole. More specifically, any accumulation of material within the retina appears as an area of elevation of different shape and size, displaying irregular and darker borders. No precise correlations between RMI, BL-AF, and NIR-AF imaging was found. RMI and FAF appear to be useful tools for characterizing retinal dystrophies. Non-invasive diagnostic tools may yield additional information on the clinical setti...Continue Reading

References

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Citations

Jan 7, 2014·Oman Journal of Ophthalmology·Martin M Nentwich, Guenther Rudolph
May 21, 2014·Saudi Journal of Ophthalmology : Official Journal of the Saudi Ophthalmological Society·Won June LeeYong Un Shin
Jul 31, 2019·The British Journal of Ophthalmology·Francesco RomanoMaurizio Battaglia Parodi
Nov 5, 2014·European Journal of Ophthalmology·Maurizio Battaglia ParodiFrancesco Bandello

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Methods Mentioned

BETA
imaging technique
imaging techniques

Software Mentioned

AF

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