Retrobulbar rhabdomyosarcoma in a budgerigar (Melopsittacus undulatus)

Avian Pathology : Journal of the W.V.P.A
M Y GulbaharM Yarim

Abstract

This report describes a retrobulbar rhabdomyosarcoma in a 7-year-old male budgerigar (Melopsittacus undulatus). The bird was presented with orbital distension and exophthalmia of the left eye and died during surgery. Necropsy revealed a tan to grey retrobulbar mass compressing all components of the left eye with obscured vision. In histopathological examination, the mass was composed of sheets of spindle-shaped cells with pleomorphic nuclei, numerous bizarre mitotic figures and mononucleated or multinucleated giant cells and also typically strap cells. Neoplastic cells had no cross-striations in sections stained by phosphotungstic acid haematoxylin. The tumour cells did not invade surrounding tissues, including the retina, and there was no metastasis to other organs. Immunohistochemically, tumour cells were positive for desmin, vimentin and alpha-smooth muscle actin, but were negative for S-100 protein and pancytokeratin.

References

Jul 1, 1966·The Journal of Pathology and Bacteriology·J G Campbell, E C Appleby
Dec 17, 2003·Avian Pathology : Journal of the W.V.P.A·H Fernández-BellonA Ramis
Jan 1, 1992·Avian Pathology : Journal of the W.V.P.A·R L Reece

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Citations

Jun 24, 2008·Avian Pathology : Journal of the W.V.P.A·G ManarollaT Rampin
Oct 11, 2013·Avian Pathology : Journal of the W.V.P.A·Csaba JakabPéter Pazár
Jan 6, 2012·Journal of Avian Medicine and Surgery·Javier G NevarezThomas N Tully
Nov 18, 2009·Journal of the American Podiatric Medical Association·Chuan YangGuojuan Lao
Feb 14, 2013·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Victoria E WatsonKaori Sakamoto
Nov 8, 2011·Journal of the American Animal Hospital Association·Laura A Snyder, Helen Michael
Jun 30, 2019·Journal of Avian Medicine and Surgery·Michala de Linde HenriksenMichelle Willette

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