PMID: 9159626May 1, 1997Paper

Retrograde cardioplegia preserves myocardial function after induced coronary air embolism

The Journal of Thoracic and Cardiovascular Surgery
A A SandhuR E Michler

Abstract

Coronary air embolism is a potential complication of cardiopulmonary bypass. We compared left ventricular function before and after the administration of antegrade or retrograde cardioplegic solution in a porcine model of coronary air embolism. Nineteen pigs were placed on cardiopulmonary bypass support and cooled to 32 degrees C. The heart was initially arrested with antegrade cold blood cardioplegic solution. The aortic crossclamp was released at 30 minutes and 0.02 cc/kg body weight of air was injected into the left anterior descending artery distal to the first diagonal branch. After 5 minutes the aorta was reclamped and the animals treated with 15 ml/kg body weight of 1:4 blood cardioplegic solution delivered by the antegrade (n = 6) or retrograde (n = 7) method. Control animals (n = 6) were not treated. Changes in regional preload recruitable stroke work were used to assess left ventricular performance before and after cardiopulmonary bypass. Two control animals could not be weaned from cardiopulmonary bypass. Left ventricular function was best preserved after treatment of induced coronary air embolism with retrograde cardioplegia (90% of baseline). Coronary air embolism treatment with antegrade cardioplegia resulted in d...Continue Reading

References

Jun 1, 1987·Journal of Cardiothoracic Anesthesia·B D SpiessA D Ivankovich
Dec 1, 1987·Anesthesiology·K J TumanA D Ivankovich
Jul 1, 1972·The Annals of Thoracic Surgery·C JusticeW S Edwards
Jul 1, 1993·The Annals of Thoracic Surgery·O J YanoC R Smith
Mar 1, 1959·Annals of Surgery·B EISEMANK PRACHUABMOH

❮ Previous
Next ❯

Citations

Dec 10, 1999·The Annals of Thoracic Surgery·N Chaudhuri, M S Hickey
Apr 20, 2001·The Annals of Thoracic Surgery·P Ruengsakulrach, B F Buxton
Nov 28, 2000·The Annals of Thoracic Surgery·M MassettiA Khayat

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.