Retroinfusion-supported stenting in high-risk patients for percutaneous intervention and bypass surgery: results of the prospective randomized myoprotect I study

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
Tilmann PohlPeter Boekstegers

Abstract

The objective of this study was to assess event-free survival and total treatment costs of retroinfusion-supported stenting in high-risk patients compared to bypass surgery. An increasing number of patients with main-stem and main-stem-equivalent stenosis are treated by stent implantation, which appears to be safe in the short-term follow-up. However, there is a lack of randomized studies comparing conventional bypass surgery with stent implantation, particularly in patients with high risk for both treatments. We here report on the 1-year results of a prospective randomized single-center study in patients with symptomatic main-stem and main-stem-equivalent lesions with substantially increased risk for bypass surgery. Patients where randomized to undergo either percutaneous transluminal coronary angioplasty/stent procedure (n = 23) or bypass surgery (n = 21). Patients randomized to stent implantation were supported by selective pressure-regulated retroinfusion of the anterior cardiac vein during ischemia. Patients of the stent group and the bypass group did not differ in baseline characteristics, including Parsonnet score and quality-of-life score. Twenty-eight-day mortality and 1-year mortality rate as well as quality-of-life s...Continue Reading

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Citations

Dec 25, 2010·Journal of Cardiovascular Translational Research·Nabil DibAnn Campbell
Feb 10, 2012·Cardiovascular Research·Rabea HinkelChristian Kupatt
Mar 21, 2013·Journal of Translational Medicine·Leo BockeriaAmit N Patel
Feb 4, 2014·Mayo Clinic Proceedings·Eoin D O'CearbhaillJeffrey M Karp
Nov 9, 2011·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Glenn N LevineUNKNOWN Society for Cardiovascular Angiography and Interventions
Dec 4, 2014·The Journal of Thoracic and Cardiovascular Surgery·Yolba SmitMassimo A Mariani
Apr 19, 2015·BMC Medical Informatics and Decision Making·Sebastian PölsterlAli Kamen
Mar 20, 2010·JACC. Cardiovascular Interventions·Nabil DibUNKNOWN International Society for Cardiovascular Translational Research
Jul 31, 2013·Expert Review of Cardiovascular Therapy·Ruben L J OsnabruggeA Pieter Kappetein
Jul 24, 2021·Journal of the American College of Cardiology·Patrick W SerruysSpencer B King Iii

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