Retroperitoneal fibrosis after chemo-radiotherapy for cervical cancer: A case report

The Journal of Obstetrics and Gynaecology Research
Yuji TakahashiJo Kitawaki

Abstract

Retroperitoneal fibrosis (RPF) is a rare disease characterized by proliferation of fibro-inflammatory tissue in the retroperitoneum. Multiple studies have reported on the idiopathic cases of the disease, but reports of RPF secondary to irradiation are very limited. Herein, we report the case of a 47-year-old woman who complained of lower abdominal pain 14 months after chemo-radiotherapy for cervical cancer. Computed tomography showed a soft-tissue mass spreading in the presacral space. Biopsy of the lesion revealed fibro-inflammatory tissue without malignancy. Retrospective imaging findings showed that the lesion was consistent with the irradiation field. We diagnosed the patient with RPF caused by radiotherapy. We started oral administration of prednisolone at a dose of 30 mg/day. After 3 months, scans showed a remarkable reduction in lesion size. Prednisolone was tapered to a maintenance dose of 5 mg/day, which is ongoing. The patient is doing well with no recurrence to date.

References

Feb 1, 1996·Rheumatic Diseases Clinics of North America·G S Gilkeson, N B Allen
Jul 8, 2000·The British Journal of Radiology·I VivasA Martínez-Cuesta
Mar 19, 2004·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·E StensvoldS D Fosså
Jan 19, 2006·Annals of Internal Medicine·Eric F H van BommelAntoine G M Zeegers
Jan 24, 2006·Lancet·Augusto VaglioCarlo Buzio
Jul 13, 2006·BJU International·Cristian P IlieDavid A Tolley
May 3, 2007·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Eric F H van BommelTadek R Hendriksz
Oct 12, 2013·Annual Review of Pathology·Vinay S MahajanJohn H Stone
Dec 3, 2014·La Revue de médecine interne·M L UrbanA Vaglio

❮ Previous
Next ❯

Citations

Jul 23, 2020·RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin·Felix PeisenSascha Kaufmann

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.

Related Papers

International Braz J Urol : Official Journal of the Brazilian Society of Urology
Ryuta WatanabeTokuhiro Iseda
European Review for Medical and Pharmacological Sciences
J-T LangN-Z Xing
Hinyokika kiyo. Acta urologica Japonica
K NishizawaN Kawamura
© 2022 Meta ULC. All rights reserved