Retroperitoneal sarcomas: a single center experience

Cancer radiothérapie : journal de la Société française de radiothérapie oncologique
Ben Hassouna JRahal K

Abstract

To analyse the management and clinical outcome of patients treated for retroperitonal soft tissue sarcoma and to identify prognosis factors. This is a retrospective study of 20 adults ; 11 women and nine men treated between 1980 and 2000 in our institution. There were seven liposarcomas and 13 leiomyosarcomas. The mean tumor size was 26 cm. Three patients underwent a complete resection (R0), 14 patients an incomplete resection (R1/R2) with microscopic or macroscopic tumour remained after surgery. Only three patients had a surgical biopsy. Median follow-up was 18 months. Overall survival rates was 45%, 10% at two and five years, respectively. Among the following factors, sex, age, symptom duration, tumor size, histologic type, histologic grade, resection type, mitotic index, necrosis extension, histologic differentiation, and AJCC stage, only mitotic index factor (scale 1,2 versus scale 3) significantly influenced patient survival (p = 0.02). This study re-emphasizes the poor outcome of patients with retroperitoneal sarcoma. Survival rates appeared low when compared with other studies. These results incite for a more aggressive approach.

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Citations

Jun 9, 2010·Canadian Journal of Dietetic Practice and Research : a Publication of Dietitians of Canada = Revue Canadienne De La Pratique Et De La Recherche En Diététique : Une Publication Des Diététistes Du Canada·Anne-Marie HamelinHuguette Turgeon O'Brien
Nov 12, 2015·World Journal of Gastroenterology : WJG·Mei Yang, Chang-Zhi Huang

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