Retrospective analysis of culture-negative versus culture-positive postoperative spinal infections

Medicine
Jae Chul LeeByung-Joon Shin

Abstract

Retrospective analysis.This study aimed to investigate the characteristics, clinical features, and outcomes of culture-negative (CN) and culture-positive (CP) postoperative spinal infections (PSIs).Causative organism cultures and the use of adequate antibiotics are essential for treating postoperative spinal wound infections. However, managing infected surgical sites with negative wound culture results is a common clinical problem. Although the outcomes of microbiologically confirmed PSIs have been well studied, the outcomes and clinical characteristics of CN PSIs have not been previously published.Between January 1995 and December 2014, 69 patients diagnosed with PSIs were enrolled. Enrolled patients were classified into 2 groups: CN (28 patients) and CP (41 patients). Baseline data, clinical manifestations, specific treatments, and treatment outcomes were compared with the groups.The overall rate of CN PSI was 40.6% (28/69). Baseline data and clinical manifestations were similar between the 2 groups. There were no significant differences in the duration of parenteral antibiotic use between the CN and CP groups. Revision surgery was required less often for the CN group (64.3%) than for the CP group (87.8%) (P = .020). Revision...Continue Reading

References

May 1, 1992·The Journal of Hospital Infection·K Twum-DansoL Wosornu
Apr 1, 1985·Spine·P R DupuisW H Kirkaldy-Willis
Feb 3, 2000·Journal of Clinical Microbiology·A GiacomettiG Scalise
Dec 5, 2006·The Journal of Bone and Joint Surgery. American Volume·Javad ParviziThomas W Bauer
Mar 8, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Todd J KowalskiDouglas R Osmon
Apr 25, 2007·Clinical Orthopaedics and Related Research·Elie GhanemRobert Barrack
Aug 19, 2007·The New England Journal of Medicine·Andrej TrampuzRobin Patel
Oct 6, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Elie F BerbariDouglas R Osmon
Dec 21, 2007·The Journal of Spinal Cord Medicine·Saad B ChaudharyMitchell F Reiter
Feb 18, 2010·Clinical Orthopaedics and Related Research·Lluís Font-VizcarraAlex Soriano
Apr 20, 2010·Clinical Orthopaedics and Related Research·Davud MalekzadehElie F Berbari
Dec 18, 2013·Surgical Neurology International·Manish K KasliwalVincent C Traynelis
Sep 4, 2015·Clinics in Orthopedic Surgery·Jin Hak KimGo We Kim
Dec 30, 2015·Asian Spine Journal·Jung Su LeeJae Il Lee
Mar 8, 2016·Asian Spine Journal·Abhijit Yuvaraj Pawar, Samar Kumar Biswas

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