Retrospective analysis of mepivacaine, prilocaine and chloroprocaine for low-dose spinal anaesthesia in outpatient perianal procedures

International Journal of Colorectal Disease
V GebhardtM D Schmittner

Abstract

Perianal procedures are carried out in an outpatient setting regularly. The purpose of this retrospective analysis was to investigate the impact of different local anaesthetics (LA) for spinal anaesthesia (SPA) on operating room (OR) efficiency (perioperative process times, turnaround times) and postoperative recovery. This study aims on the determination of the optimal LA for low-dose SPA in the specific setting of a high-volume day-surgery centre. Anaesthesia records of all patients undergoing perianal outpatient surgery under saddle-block SPA at the Mannheim University Medical Centre from 2008 until 2017 were analysed. Patients were categorized as having received prilocaine, mepivacaine or chloroprocaine. Two thousand seven hundred forty-six patients were included. Postoperative recovery was faster for chloroprocaine 1% compared with both other LAs. Preoperative processes but not process times in the OR were shorter for chloroprocaine. In contrary, turnaround times were significantly prolonged when chloroprocaine had been used, leading to reduction of OR efficiency. Low-dose SPA provides reliable blocks for perianal surgery. Considerations on the choice of LA for SPA must include not only the recovery profile, but also the i...Continue Reading

References

Feb 1, 1995·Journal of Clinical Anesthesia·J A Aldrete
May 26, 2005·Anesthesiology·Franklin DexterJohannes Ledolter
Sep 9, 2006·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Imad T Awad, Frances Chung
Nov 9, 2007·Current Opinion in Anaesthesiology·Paul F White, Matthew Eng
Apr 17, 2009·The Cochrane Database of Systematic Reviews·Dusanka Zaric, Nathan Leon Pace
Nov 29, 2012·ANZ Journal of Surgery·Bishoy A B SolimanShekib Shahbaz
Aug 8, 2013·World Journal of Gastroenterology : WJG·Jun YangDa-Nian Tong
Mar 15, 2014·European Journal of Anaesthesiology·Dietrich DollChristian Hoenemann
Apr 16, 2014·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Hong-lei ChenJun-sheng Peng
Mar 19, 2016·Anesthesia and Analgesia·Markus M LuediDietrich Doll
Jun 30, 2016·Anaesthesia Critical Care & Pain Medicine·Jan BoublikArthur Atchabahian
Nov 29, 2016·Acta Anaesthesiologica Scandinavica·V GebhardtM D Schmittner
Dec 6, 2016·Anesthesia and Analgesia·Dietrich DollMarkus M Luedi
Jan 27, 2018·Sultan Qaboos University Medical Journal·Regula MorgeneggDietrich Doll
Mar 27, 2018·Acta Anaesthesiologica Scandinavica·E K AasvangH Kehlet

❮ Previous
Next ❯

Citations

Oct 2, 2020·Current Opinion in Anaesthesiology·Jesse StewartGirish P Joshi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.