Retrospective analysis of unstaged and staged Gamma Knife surgery with and without preceding embolization for the treatment of arteriovenous malformations

Journal of Neurosurgery
Adam G BackPeter M Shedden

Abstract

The authors conducted a retrospective study to examine data on rates of obliteration of arteriovenous malformations (AVMs) with use of various combinations of treatment modalities based on Gamma Knife surgery (GKS). The authors believe that this study is the first to report on patients treated with embolization followed by staged GKS. The authors identified 150 patients who underwent GKS for treatment of AVMs between 1994 and 2004. In a retrospective study, 4 independent groups emerged based on the various combinations of treatment: 92 patients who underwent unstaged GKS, 28 patients who underwent embolization followed by unstaged GKS, 23 patients who underwent staged GKS, and 7 patients who underwent embolization followed by staged GKS. A minimum of 3 years of follow-up after the last GKS treatment was required for inclusion in the retrospective analysis. Angiograms, MR images, or CT scans at follow-up were required for calculating rates of obliteration of AVMs. Fifty-seven of 150 patients (38%) supplied angiograms, and overall obliteration was confirmed in 43 of these 57 patients (75.4%). An additional 37 patients had follow-up MR images or CT scans. The overall obliteration rate, including patients with follow-up angiograms ...Continue Reading

Citations

Dec 19, 2013·Surgical Neurology International·Emerson Magno de AndradeSalomon Benabou
Aug 27, 2015·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Fred A ZeilerMichael West
Oct 28, 2011·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·F A ZeilerM West
Jan 1, 2015·Nature Reviews. Disease Primers·Michael T LawtonRobert F Spetzler
Jan 10, 2014·Neurosurgery·Benjamin A RubinDouglas Kondziolka
Jan 10, 2014·Neurosurgery·R Webster CrowleyFelipe C Albuquerque
Oct 21, 2016·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Stefan KnippenRainer Fietkau
May 12, 2019·Neurosurgery·Dale DingJason P Sheehan

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