Abstract
The study objective was to explore the relationship between necrotizing enterocolitis (NEC) and packed red blood cell (pRBC) transfusion in very low birth weight (VLBW) neonates (<1500 g). A six-year retrospective chart review of VLBW infants with NEC (Bell's Stage > II) and a pRBC transfusion within 48 hours of diagnosis. Prenatal data, postnatal course, transfusion history, and NEC outcomes were reviewed. The transfusion associated necrotizing enterocolitis (TANEC) cases were matched with controls (1:2) who were transfused but did not develop NEC as to proximity of birth date, gestational age, and receipt of transfusion. Of 1139 VLBW admissions, there were 73 cases of NEC and 30 cases of TANEC (annual NEC rate 6.4%). TANEC cases were matched with 60 controls who were transfused but never developed NEC. Neonatal profiles were similar between all 3 groups, except for a higher proportion of infants <10th percentile in the non-TANEC group. Days of antibiotics and frequency of patient ductus arteriosus (PDA) ligation were lower in controls compared to NEC cases. Lower feeding rate at diagnosis of NEC/match were more common in control infants compared to TANEC infants. However, feeding abstinence rates were similar between the two ...Continue Reading
References
Mar 5, 2002·Pediatrics·Jennifer A BisqueraCarol Lynn Berseth
Dec 24, 2002·Archives of Disease in Childhood. Fetal and Neonatal Edition·W McGuire, M Y Anthony
Mar 3, 2005·Pediatrics·Susan R HintzUNKNOWN NICHD Neonatal Research Network
Sep 30, 2006·American Journal of Perinatology·Pradeep MallyEdmund F LaGamma
Oct 10, 2006·Lancet·Patricia W Lin, Barbara J Stoll
Oct 21, 2006·Paediatric and Perinatal Epidemiology·Robert C HolmanLawrence B Schonberger
Aug 22, 2008·Journal of Perinatology : Official Journal of the California Perinatal Association·J Meinzen-DerrE F Donovan
Nov 21, 2008·American Journal of Perinatology·Gretchen A KrimmelToby Debra Yanowitz
Dec 11, 2008·Neonatal Network : NN·Patti Schurr, Esther M Perkins
May 2, 2009·Neonatology·Michael Obladen
Nov 12, 2010·The Journal of Pediatrics·Jonathan BlauEdmund F La Gamma
Jan 21, 2011·The New England Journal of Medicine·Josef Neu, W Allan Walker
Jan 22, 2011·Journal of Perinatology : Official Journal of the California Perinatal Association·M El-DibH Aly
Jan 29, 2011·Journal of Perinatology : Official Journal of the California Perinatal Association·R SinghD M Kent
Mar 16, 2011·Pediatrics·David A PaulRobert G Locke
Feb 22, 2012·Pediatrics·Adel Mohamed, Parkesh S Shah
Jul 24, 2012·Seminars in Perinatology·Edmund F La Gamma, Jonathan Blau
Feb 19, 2013·Clinics in Perinatology·Renu Sharma, Mark Lawrence Hudak
May 25, 2013·Journal of Perinatology : Official Journal of the California Perinatal Association·P Wan-HuenE Parravicini
Jan 21, 2014·Journal of Neonatal-perinatal Medicine·F Gómez MartínJ Quero Jiménez
Mar 7, 2014·Early Human Development·Chris DerienzoC Michael Cotten
Jun 21, 2014·The Journal of Pediatrics·Terri MarinJames E Moore
Jul 21, 2014·The Journal of Pediatrics·Matthew B WallensteinValerie Y Chock
Mar 5, 2016·JAMA : the Journal of the American Medical Association·Ravi M PatelCassandra D Josephson
Citations
Feb 6, 2021·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Dan ArbellSaul Yedgar
May 4, 2021·Advances in Neonatal Care : Official Journal of the National Association of Neonatal Nurses·Emma Killion
Mar 7, 2021·Advances in Neonatal Care : Official Journal of the National Association of Neonatal Nurses·Leslie A ParkerMarina Magalhães
May 23, 2020·Clinics in Perinatology·Allison Thomas RoseRavi Mangal Patel