Retrospective observational evaluation of postoperative oxygen saturation levels and associated postoperative respiratory complications and hospital resource utilization

PloS One
Satya Krishna RamachandranAmy M Shanks

Abstract

The clinical importance of postoperative episodic hypoxemia is still unclear, and therefore largely under-studied. As a result, there is limited understanding of its relationship with early postoperative respiratory complications (PRC, defined as intubation within three days of surgery) and hospital resource utilization. This single center study was performed using a retrospective observational design. We described population based definitions of desaturation from continuous SpO2 monitoring data captured in the post anesthesia care unit (PACU), namely median SpO2 in PACU, duration of desaturation below median, nadir desaturation, and length of oxygen therapy relative to PACU duration. These measures were evaluated against the occurrence of early PRC in logistic regression models. Measures that were independently associated with early PRC were accepted as the primary study exposures. Stratified logistic regression models were planned if significant interaction occurred with high risk surgical procedures. Models were adjusted by including several patient conditions, procedural, and anesthesia risk factors. Propensity matching on desaturation occurrence was planned to evaluate the relationship with postoperative resource utilizati...Continue Reading

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Citations

Apr 22, 2020·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Cassandra L PuccinelliKathryn M Van Abel
Sep 19, 2019·Acta Anaesthesiologica Scandinavica·Flora T ScheffenbichlerMatthias Eikermann
Jul 14, 2020·Acta Anaesthesiologica Scandinavica·In-Ae SongDa-Yun Lee
Apr 22, 2021·BMC Research Notes·Jeremy JuangAlvaro Andres Macias

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