Retrospective review of Arctic Front Advance Cryoballoon Ablation: a multicenter examination of second-generation cryoballoon (RADICOOL trial)

Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing
Wilber W SuPaul J Wang

Abstract

Pulmonary vein isolation (PVI) via catheter ablation is an approved therapy for patients with drug-refractory and symptomatic atrial fibrillation (AF). Furthermore, cryoballoon is now considered to be as effective as focal radiofrequency catheter ablation. This study examines the second-generation cryoballoon performance in a US multicenter review of real-world practices. By retrospective chart collections, the long-term efficacy and safety of the cryoballoon procedure were assessed in 15 US centers. All patients had a history of drug-refractory symptomatic paroxysmal AF and were treated with a cryoballoon PVI strategy at the index ablation. Four hundred fifty-two patients were evaluated, and acute PVI was achieved in 99% of patients by cryoballoon catheter ablation. In 0.88% of patients (4/452), an additional focal ablation catheter was used to achieve acute PVI during the ablation procedure. Average procedure time was 128 (range 82 to 260) min, using an average of 17 (range 1 to 19) min of fluoroscopy. The most frequent adverse event was transient phrenic nerve injury (1.5%; 7/452 patients) which all resolved by the end of the procedure with no diaphragmatic dysfunction at discharge. There were no strokes, transient ischemic ...Continue Reading

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Citations

Nov 18, 2018·Current Opinion in Cardiology·Emrie Tomaiko, Wilber W Su
Apr 11, 2018·Arrhythmia & Electrophysiology Review·Nitin KulkarniRichard Wu
May 18, 2020·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Philipp SeidlAnja Schade
Jan 31, 2020·Circulation Reports·Kazuyoshi SuenariShih-Ann Chen
May 27, 2020·Cardiac Electrophysiology Clinics·Rahul BhardwajSrinivas R Dukkipati
Sep 9, 2020·Archives of Cardiovascular Diseases·Camille PichardRaphaël P Martins

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