Retrospective Review of Folliculitis Decalvans in 23 Patients with Course and Treatment Analysis of Long-standing Cases

Journal of Cutaneous Medicine and Surgery
M J Kristine BunaganJerry Shapiro

Abstract

To date, there is no standard treatment of folliculitis decalvans (FD), a rare type of cicatricial alopecia. The records of 23 patients with FD (1998-2012) were retrospectively analyzed, with added data review on the course and treatment of long-standing cases. Initial management consisted mostly of intralesional triamcinolone acetonide, clobetasol lotion, and either cephalexin, minocycline, doxycycline, or tetracycline. Alternatives consisted of rifampicin, clindamycin, ciprofloxacin, and isotretinoin. Remission was achieved in weeks to months in more than half of the cases, with low occurrence of relapse. The poor responders had a protracted course of temporary improvement and multiple relapses. The majority of patients showed improvement and subsequent remission with oral antibiotics. In some patients, it took years of slow taper before the antibiotic could be discontinued. Only a few patients had recalcitrant disease, with minimal response to their initial and alternative medications.

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Citations

Dec 23, 2015·Actas dermo-sifiliográficas·B MonteagudoA M Porta
Oct 18, 2019·The Australasian Journal of Dermatology·Anes YangSteven Kossard
Jul 6, 2020·Dermatologic Therapy·Rebekka JerjenRodney Sinclair
Jan 10, 2018·International Journal of Dermatology·Berna AksoyEmine Mutlu
Apr 3, 2018·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Andy C Hsi, Ilana S Rosman
May 29, 2021·Photodiagnosis and Photodynamic Therapy·Lun YangAiyuan Guo

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Methods Mentioned

BETA
biopsy

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