PMID: 9524948Apr 3, 1998Paper

Retroviral sequence located in border region of short unique region and short terminal repeat of Md5 strain of Marek's disease virus type 1

The Journal of Veterinary Medical Science
D EndohM Kuwabara

Abstract

A 246-base pair (bp) retroviral sequence, which was homologous to a long terminal repeat of avian erythroblastosis virus (AEV), was detected and cloned from Md5 strain (Md5) of Marek's disease virus type 1 (MDV1) by representational difference analysis (RDA). The retroviral sequence was thought to be located in the border region of short unique region (U(s) and short terminal repeat (TRs), but did not exist in the border region of U(s) and the inverted short repeat (IRs) of the Md5 genome. A cloned fragment of the US/TRs border region of the Md5 genome showed a construction of U-E'-R-U'-E-TRs with the regions designated as follows: E, expanded TRs reported by Jones et al. [Proc. Natl. Acad. Sci. U.S.A. 90, 3855, 1993]; E', a partial copy of the expanded TRs; R, the retroviral sequence detected in Md5 genome; U, TRs-end sequence of U(s); U', a partial copy of TRs-end sequence of U(s). The sequence unit indicated as E'-R-U' was thought to be heterogeneously repeated in the Md5 genome. Since this retroviral sequence reportedly did not exist in the original stock of Md5, the retroviral sequence is thought to be inserted in the Md5 genome without experimental co-infection of avian cells with retrovirus and MDV1. These results sugges...Continue Reading

References

Jan 24, 1979·Medical Microbiology and Immunology·C Kaschka-DierichR Thomssen
Oct 1, 1979·The Journal of General Virology·K HiraiS Kato
Dec 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·F SangerA R Coulson
Feb 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·R IsfortH J Kung
Mar 1, 1990·Journal of Virological Methods·R J IsfortH J Kung
Jan 1, 1986·Critical Reviews in Microbiology·B W Calnek
Jan 1, 1985·Advances in Virus Research·S Kato, K Hirai
Mar 1, 1971·Journal of Virology·L F LeeK Nazerian
Jun 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·Y K FungH J Kung
Jan 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·J CebrianP Sheldrick
Jul 1, 1984·Journal of Virology·K FukuchiM Nonoyama
May 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·D JonesH J Kung
Feb 12, 1993·Science·N LisitsynM Wigler
Jan 1, 1995·Virus Genes·P Brunovskis, H J Kung

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Citations

Apr 27, 2016·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Hongchao LvChangjun Liu
Aug 6, 2020·Animals : an Open Access Journal From MDPI·Irit Davidson

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