Retroviruses and reproduction revisited

Journal of Assisted Reproduction and Genetics
Ann A Kiessling

Abstract

Thanks to effective anti-HIV medications, deaths from acquired immunodeficiency disease (AIDS) have plummeted, although the incidence of new HIV infections has decreased little, approximately 36,000 annually in the USA. The CDC estimates 1.1 million persons, mostly men, are living with HIV in the USA, with approximately 14% unaware they are infected. Since the global blood supply is essentially free of HIV today, infected semen is fueling the pandemic (88% of new infections in the USA), with needle sharing among IV drug abusers (7% of new US infections) and female to male transmission (5% of new infections) accounting for the balance. In spite of the importance to disease prevention and strategies for safe conception, semen transmission of HIV is not well understood. Because anti-HIV therapy does not eliminate HIV from semen, the Centers for Disease Control (CDC) for the past 25 years has espoused condom use as the safest approach to prevent HIV transmission, as well as other sexually transmitted diseases. A few months ago, however, an MMWR was circulated by the CDC that suggested condomless sex might be safe if the HIV-infected partner's medications achieved an undetectable viral load in his blood. This new opinion was based o...Continue Reading

References

May 1, 1989·Fertility and Sterility·A A Kiessling
May 3, 2001·The New England Journal of Medicine·S B BoppanaW J Britt
Feb 25, 2003·JAMA : the Journal of the American Medical Association·Karen B FowlerRobert F Pass
Jan 31, 2009·The Lancet Infectious Diseases·Marie-Claude BoilyMichel Alary
Feb 10, 2011·Journal of Translational Medicine·Jean-Charles GrivelLeonid B Margolis
Oct 22, 2011·Journal of Reproductive Immunology·Walter Cardona-MayaMaría T Rugeles
Dec 10, 2013·Fertility and Sterility·Joshua LuptonAnn A Kiessling
Jan 5, 2014·Current Opinion in HIV and AIDS·Mary K Grabowski, Andrew D Redd
Nov 22, 2014·The Journal of Infectious Diseases·Laurent HouzetNathalie Dejucq-Rainsford
Jul 13, 2016·JAMA : the Journal of the American Medical Association·Alison J RodgerUNKNOWN PARTNER Study Group
Jul 19, 2016·The New England Journal of Medicine·Myron S CohenUNKNOWN HPTN 052 Study Team
Aug 9, 2016·Nature Medicine·Katherine M BrunerRobert F Siliciano
Nov 14, 2016·JAMA : the Journal of the American Medical Association·Jason D GoldmanJames I Mullins
Dec 1, 2017·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Alain VandormaelFrank Tanser

❮ Previous
Next ❯

Citations

Feb 8, 2020·Physiological Reviews·Anna Le TortorecNathalie Dejucq-Rainsford

❮ Previous
Next ❯

Related Concepts

Related Feeds

Addiction

This feed focuses mechanisms underlying addiction and addictive behaviour including heroin and opium dependence, alcohol intoxication, gambling, and tobacco addiction.

Related Papers

JAMA : the Journal of the American Medical Association
Eric S Daar, Katya Corado
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Mina HosseinipourAngela D M Kashuba
© 2022 Meta ULC. All rights reserved